下丘脑错构瘤术后青春期再启动  

Resumption of normal onset of puberty after resection of hypothalamic hamartoma

作　　者：罗世琪[1] 李春德[1] 马振宇[1] 甲戈[1] 张玉琪[1] 

机构地区：[1]首都医科大学附属北京天坛医院神经外科,100050

出　　处：《中华神经外科杂志》2010年第5期438-440,共3页Chinese Journal of Neurosurgery

摘　　要：目的探讨手术切除下丘脑错构瘤对正常青春期启动的影响。方法对早年手术切除下丘脑错构瘤治疗单纯性早熟的3例女孩进行长期随访，观察再次青春期启动时间、身体及智力发育情况。结果3例女孩术后性早熟停止，直至在术后8．0年、8．3年及7．5年后再次来月经并规律，身高、体质量及智力均正常。结论下丘脑错构瘤可能为异位的“副下丘脑”，手术切除下丘脑错构瘤对正常青春期启动无明显影响。Objective To study the effect of the resection of hypothalamic hamartoma （HH） on the normal start of puberty. Method Three girls whose HHs were totally removed were followed -up for long term to study the onset of spontaneous menses, general health and the development of intelligence. Results The precocious puberty was arrested immediately after the resection of HH in three girls and the start of spontaneous menses were begun in the 8. 0th ,8. 3th and 7. 5th years postsurgery with regular menses. The height stature ,body weight and intelligence development were all normal. Conclusions The hypothalamic hamartoma may be a eetopic ＂second hypothalamus＂ and the resection of HH may have no effects on the normal start of puberty.

关 键 词：下丘脑 错构瘤 术后 青春期再启动 

分 类 号：R739.4[医药卫生—肿瘤]