α,β-不饱和糖烯醛的合成  

Synthesis of the α,β-Unsaturated Sugar Aldehyde

作　　者：李小六[1] 王艳飞[1] 焦玲玲[1] 王怡玫[2] 冯俊娜[1] 殷庆梅[1] 陈华[1] 张平竹[1] 

机构地区：[1]河北大学化学与环境科学学院河北省化学生物学重点实验室,河北保定071002 [2]河北大学生命科学学院,河北保定071002

出　　处：《河北大学学报（自然科学版）》2010年第3期259-263,共5页Journal of Hebei University(Natural Science Edition)

基　　金：河北省自然科学基金资助项目(B2008000588);河北省科技指导计划项目(09276418D-13);河北省教育厅计划项目(2009309)

摘　　要：为探讨α,β-不饱和糖烯醛的最佳合成条件,以五、六元糖醛为起始原料,在不同温度下合成了该类化合物.结果表明,高温有助于消除反应的进行.进一步探讨了糖氧化合成不饱和糖烯醛的反应,并首次实现了由苄基保护的糖向不饱和糖烯醛的一步合成.For approaching the synthesis of α,β-unsaturated sugar aldehyde,a series of α,β-unsaturated sugar aldehyde was synthesized under different tempratures with five or six menbered sugar aldehyde as starting materials.The results showed that the elimination reaction would be promoted under high temperature.Furthermore,the synthesis of α,β-unsaturated sugar aldehyde via oxidation reaction was explored.The corresponding α,β-unsaturated sugar aldehyde protected by benzyl was firstly obtained by one step synthesis.

关 键 词：不饱和糖烯醛 消除反应 氧化 苄基 

分 类 号：O621.3[理学—有机化学]