血清肿瘤相关物质检测在恶性肿瘤诊断中的应用价值  

Diagnostic value of boxin serum tumor associated material(BXTM) for maglignant tumor

作　　者：王君哲[1] 牟君成[1] 范慧[1] 程联[1] 

机构地区：[1]重庆三峡中心医院,重庆万州404000

出　　处：《重庆医学》2010年第11期1418-1419,共2页Chongqing medicine

摘　　要：目的探讨肿瘤相关物质(BXTM)检测在恶性肿瘤诊断中的应用价值。方法采用生化法对155例恶性肿瘤患者(A组),103例非肿瘤患者(B组)和1 000名健康体检人员(C组)的BXTM浓度进行检测。结果 BXTM含量:A组(100.84±13.08)u/mL明显高于B组(86.67±10.33)u/mL和C组(81.45±9.69)u/mL,差异均有统计学意义(P<0.01)。BXTM测定恶性肿瘤的敏感性(真阳性数/患者受试者数×100%)为73.55%,自身免疫系统疾病、良性肿瘤以及健康体检者的特异性(真阴性数/无恶性肿瘤者数×100%)分别为68.75%、82.35%和98.4%。结论 BXTM检测对恶性肿瘤的早期辅助诊断,良、恶性肿瘤的鉴别诊断以及人群普查有较为重要的价值,具有很高的敏感性、特异性和广谱性。Objective To investigate the diagnostic value of Boxin serum Tumor associated Material（BXTM） for malignant tumor.Methods The level of BXTM was measured in 155 cases of malignant tumor（A group）,103 cases of non malignant tumor（B group） and 1 000 cases normal people（C group）.Results The level of BXTM of A group（100.84 ±13.08）u/mL was significantly higher than B group（86.67 ±10.33）u/mL and C group（81.45±9.69）u/mL（P〈0.01）.The sensibility of malignant tumors was 73.55%,and the specificities of benign tumors and normal people were 82.85% and 98.4%,respectively.Conclusion It has been testified that the measurement on the content of BXTM has important clinical values in early diagnosis of tumor,differential diagnosis of benign and malignant tumors,and mass survey.

关 键 词：肿瘤相关物质 肿瘤 诊断 

分 类 号：R730.43[医药卫生—肿瘤]