不同级别少突胶质细胞瘤MRI表现与病理相关性分析  

Correlative Analysis between MRI Manifestations and Pathological Features of Oligodendrogliomas in Different Grades

作　　者：马成[1] 王倩[2] 任静[1] 徐俊卿[1] 印弘[1] 郝跃文[1] 冯晨[1] 袁远[1] 齐顺[1] 汤丽华[1] 

机构地区：[1]第四军医大学西京医院放射科,陕西西安710032 [2]南方医科大学南方医院超声科

出　　处：《实用放射学杂志》2010年第5期620-623,共4页Journal of Practical Radiology

摘　　要：目的 分析不同级别少突胶质细胞瘤的MRI表现与病理分型的相关性.方法 回顾性分析经病理证实的50例少突胶质细胞瘤MRI表现.结果 WHOⅡ级者占30例,中位年龄36岁,肿瘤均发生于幕上,侧脑室及斜坡各1例,7例呈侵袭性生长,无包膜,7例出血,5例囊变.26 例T1WI呈低信号,4例呈等信号,30例T2WI呈高信号,增强扫描10例呈轻度强化,17例呈中度强化,3例明显强化;WHOⅢ级者占19例,中位年龄40岁,6例呈侵袭性生长,9例囊变,8例出血,16例T1WI例呈低信号,3例呈等信号, 16 例T2WI呈高信号, 2例呈等信号,1例呈低信号,增强扫描轻度强化2例,3例中度强化,14例呈明显强化;WHOⅣ级者占1例,男性,发生于顶叶,T1WI呈低信号,T2WI呈高信号,增强扫描明显强化.瘤体周变水肿以WHOⅢ级最为明显.结论 不同级别的少突胶质细胞瘤在年龄、性别、好发部位及生长方式无明显差异.但在MRI信号、瘤周水肿及强化方式方面存在差异.Objective To analyse the correlation between MRI characteristics and pathological grade m dillerent grade ohgodendroglioma. Methods MRI manifestations of pathologically diagnosed oligodendrogliomas in 50 cases were anaysed retrospectively. The differences among ages,sex and MRI characteristics were compared in different grade tumors. Results Of all 50 oligodendrogliomas,30 were grade Ⅱ according to WHO criteria,which were liable to be found in middle-aged male with the median age of 36. The tumors were all found in supratentorial, mainly in frontal and temporal lobes,some were found in lateral ventricle and clivus. The tumors in 7 cases grew diffusively without envelope and manifested hemorrhage,cystic changes. The tumors in 26 cases appeared as hypointensity and in 4 cases appeared as isointensity on T1 WI, in 30 cases appeared as hyperintensity on T2 WI. On post--contrast enhanced images, the tumors were slight enhancement in 10, mid enhancement in 17 and strong enhancement in 3.19 cases were grade III,which were liable to be found in female in any age , the tumors were mainly in frontal lobes and grew diffusively in 6,cystic changes in 9 and hemorrhage in 8,16 cases appeared as hypointensity and 3 cases appeared as isointensity on T1WI,16 cases appeared as hyperintensity, 2 cases appeared as isointensity and 1 case appeared as hypointensiyt on T2 WI;on post--contrast enhanced images, 2 cases displayed slight enhancement, 3 cases displayed mid enhancement and 14 cases displayed strong enhancement. 1 case were grade IV in a man and found in parietal lobe,the tumor displayed hypointense on T1 WI and hyperintense on T2WI with obviously enhancement. In 50 cases with oligodendrogliomas,parenchyma edema around the tumors was most significant in grade Ⅲ cases. Conclusion Oligodendrogliomas in different grades exist significant differences among age, sex, predilection site, MRI signal,growth pattern and enhancement pattern.

关 键 词：脑 少突胶质细胞瘤 磁共振成像 病理 

分 类 号：R739.41[医药卫生—肿瘤] R445.2[医药卫生—临床医学]