还原型谷胱甘肽并用L-肉碱治疗急性病毒性心肌炎的临床效果  

Therapeutic effect of reduced glutathione and L-carnitine on acute viral myocarditis

作　　者：顾秀莲[1] 王玲[1] 潘瑞麟[1] 巢胜吾[1] 樊济海[1] 

机构地区：[1]解放军第455医院心内科,上海200052

出　　处：《心脏杂志》2010年第3期403-405,共3页Chinese Heart Journal

摘　　要：目的:观察还原型谷胱甘肽并用L-肉碱治疗急性病毒性心肌炎的临床效果。方法:选择急性病毒性心肌炎患者70例,随机分为两组:对照组(35例)给予黄芪注射液、维生素C等常规药物治疗;试药组(35例)在常规治疗的基础上加用还原型谷胱甘肽以及L-肉碱治疗。结果:试药组临床治愈率为69%,对照组临床治愈率46%,两组比较有统计学差异(P<0.05);试药组左室射血分数较对照组比较显著改善(P<0.05);未发现与药物相关的不良反应。结论:还原型谷胱甘肽并用L-肉碱能明显提高治疗急性病毒性心肌炎的临床疗效。AIM： To observe the therapeutic effect of reduced glutathione and L-carnitine on acute viral myocarditis. METHODS： Seventy patients with viral myocarditis were randomly divided into therapy group and control group. Control group received routine treatment and therapy group received reduced glutathione and L-carnitine in addition to routine treatment. RESULTS： In the therapy group, 69% of the cases recovered compared with 46% of the cases in the control group （ P 〈 0. 05 ）. Heart function in the therapy group improved significantly compared with that in the control group （P 〈 0.05 ）. No adverse effect in the therapy group was found. CONCLUSION： Reduced glutathione and L-carnitine combined with routine therapy is safe and effective in the treatment of viral myocarditis.

关 键 词：还原型谷胱甘肽 肉碱 心肌炎 病毒性 

分 类 号：R542.2[医药卫生—心血管疾病]