癫患儿共患焦虑障碍的发病情况和临床特征  

Prevalence and Characteristics of Anxiety Disorder in Children with Epilepsy

作　　者：张大华[1] 秦炯[1] 韩颖[1] 姜玉武[1] 包新华[1] 张月华[1] 林庆[1] 

机构地区：[1]北京大学第一医院儿科,北京100034

出　　处：《实用儿科临床杂志》2010年第11期851-853,共3页Journal of Applied Clinical Pediatrics

摘　　要：目的探讨癫患儿共患焦虑障碍的发病情况和临床特征。方法采用儿童焦虑性情绪障碍筛查量表(SCARED),对2009年12月-2010年4月在北京大学第一医院儿科就诊的165例7～16岁癫患儿进行筛查,以SCARED量表分≥23分者视为焦虑障碍。采用SPSS14.0软件对不同性别、不同年龄组的癫患儿共患焦虑障碍情况进行χ2检验,对其分值进行秩和检验。结果 1.在筛查的165例癫患儿中,焦虑障碍总体共患率为27.3%(45/165例);女童(25例,37.3%)明显高于男童(20例,20.4%),差异有统计学意义(χ2=5.734,P<0.05)。7～12岁学龄儿童共患焦虑障碍38/138例(27.5%),13～16岁青春期儿童7/27例(25.9%),2个年龄组比较差异无统计学意义(χ2=0.000,P>0.05)。2.对不同性别癫患儿SCARED筛查结果进行比较,在各项目分、5个因子分及总分几个方面,女童得分均高于男童,其中7个项目分(第3、4、10、26、32、35、39小项目),2个因子分(广泛性焦虑、社交恐怖)及总分存在统计学差异(Pa<0.05)。3.对7～12岁、13～16岁2个年龄组癫患儿进行比较,在总分上差异无统计学意义,但在个别小项目上,如量表中第13条(我总担心让我一个人睡觉),7～12岁年龄组癫患儿分值明显高于13～16岁年龄组的癫患儿,差异有统计学意义(P<0.01)。结论癫患儿共患焦虑障碍的发生率较高,女童更易发生焦虑障碍,应加强对癫患儿精神心理状况的关注。Objective To investigate the prevalence and characteristics of anxiety disorder in children with epilepsy. Methods Screen for child anxiety related emotional disorders（SCARED） was used,and 165 children with epilepsy in Department of Pediatrics,Peking Univer- sity First Hospital from Dec. 2009 to Apr. 2010, aged 7 - 16 years old, were enrolled for screening. A positive result was defined as SCARED≥ 23 scores,and anxiety co - morbidity was considered. SPSS 14.0 software was used to conduct chi square test on different gender,different age groups suffering from anxiety disorders in children with epilepsy and the corresponding values were statistically analyzed by using rank sum test. Results 1. The total anxiety disorder co - morbidity rate in this group was 27.3% （ n = 45 ）, with a much higher rate in girls（ n = 25, 37. 3% ）than that in boys（ n = 20,20.4% ） （X2 = 5. 734, P 〈 0.05 ）. The total anxiety disorder eomorbidity rate in children aged 7 - 12 years old （27.5 % ） and that in aged 13 - 16 years old （25.9%） had no significant differences （X2 = 0. 000,P 〉 0.05 ）. 2. SCARED scores （ inclu- ding total scores,those of all items and 5 factors） were higher in girls than that in boys, and those of 7 items （ 3,4,10,26,32,35,39 ） and 2 factors（ generalized anxiety,social phobia）（P 〈 0.05 ）. 3. No significant differences of anxiety comorbidity rates were demonstrated between the children aged 7 - 12 years old and those aged 13 - 16 years old,some differences existed in a few single items though. For example,in the 13rd item（ I am always worried obout sleeping alone） （ P 〈 0.01 ）. Conclusions The preliminary data of the present study indicated that chil- dren,particularly the girls with epilepsy,are at a higher risk of anxiety disorder. Particular attention should be paid to anxiety problems in the clinical practice of pediatric epileptology.

关 键 词：癫痈 焦虑 儿童 

分 类 号：R742.1[医药卫生—神经病学与精神病学]