内镜智能分光比色技术诊断结肠肿瘤性病变的临床研究  

A study of Fuji Intelligent Chromo Endoscopy in the diagnosis of colonrectai neoplasia

作　　者：徐宁[1] 刘运祥[1] 黄留业[1] 吴承荣[1] 崔俊[1] 

机构地区：[1]山东省烟台市毓璜顶医院消化内科,264000

出　　处：《中国临床实用医学》2010年第6期1-3,共3页China Clinical Practical Medicine

基　　金：山东省自然科学基金资助项目（项目编号：Y2007C120）

摘　　要：目的探讨内镜智能分光比色技术（FICE）在诊断结肠肿瘤性病变的价值。方法选择2009年1月至2010年2月期间共781例患者进行常规内镜检查，其中发现结肠新生物或息肉样病变者共236例入选。分别采用常规放大技术、FICE放大技术及染色放大技术对病变进行腺管开口分型及微血管形态观察，对病变作出诊断，并与病理组织学诊断相比较。结果在236例患者中发现新生性病变431个，其中常规放大内镜下发现病变392个（91．0％），FICE放大模式下发现病变FICE放大内镜发现病变421个（97．9％），二者比较差异有统计学意义。FICE放大内镜比染色放大内镜更能清晰显示黏膜微血管结构形态（P〈0．01），在显示腺管开口方面两者差异无统计学意义。FICE放大内镜对肿瘤性及非肿瘤性判断符合率为符合率90．7％，高于染色放大内镜82．3％（P〈0．01）。结论FICE放大内镜可以观察黏膜表面微细结构及微血管形态，对结肠肿瘤性及非肿瘤性病变诊断的符合率高于普通放大内镜及染色放大内镜，有利于结肠早期癌的发现，有良好的I临床应用价值。Objective To investgate the value of Fuji Intelligent Chromo Endoscopy（FICE） for the diagnosis of colonrectal neoplasia. Methods 781 patients were examined with ordinary colonoscopy from Janury in 2009 to February in 2010. 236 patients with colon neoplasm or polypoid lesion were enrolled in this study. The patients were examined with magnifying conventional colonoscopy, magnifying FICE technique and magnifying chromoendoscopy technique, the pit pattern and blood capillary form of the lesion were examined. The endoscop- ic diagnosis was made,and compared with pathologic diagnosis. Resiflts 431 neoplasms were detected in the 236 patients,among those 91.0% were detected with magnifying conventional endoscopy, 97. 9% were detected with FICE technique, there was significant difference between the two methods. FICE could more clearly show the structure and form of mucosal blood capillary than chromoendoscopy technique, （ P 〈 0. 01 ） , there was no significant difference between the two methods for showing the pit pattern. The coincident rate of FICE for the di- agnosis of tumor and non-tumor lesions was 90. 7%, which was significant higher than that of chromoendoscopy 82.3% （P 〈0.01 ）. Conclusion Magnifying FICE endoscopy could show mucosal microstructure and blood capillary form. It has the superiority of high coincident rate in distinguishing neoplastic from non-neoplastic colo- rectal lesions compared with conventional magnifying colonoscopy and magnifying chromoendoscopy. The detec- ted rate of early carcinoma of colon is dramatically increased with FICE. FICE could be easily operated, and have satisfactory clinical practical value

关 键 词：智能分光比色技术 结肠肿瘤 诊断 

分 类 号：R735.34[医药卫生—肿瘤]