肿瘤的微环境疗法  

A New Approach to Treatment Cancer-microenvironment Therapy

作　　者：董超[1] 张天禹[1] 谭宁[2] 

机构地区：[1]桂林医学院附属医院泌尿外科,广西桂林541001 [2]桂林医学院生物技术学院,广西桂林541001

出　　处：《医学综述》2010年第12期1804-1806,共3页Medical Recapitulate

基　　金：广西壮族自治区卫生厅医疗卫生重点科研课题(200982);广西壮族自治区卫生厅科研课题(Z2007320);科技部癌基因及相关基因国家重点实验室开放课题(90-08-01)

摘　　要：肿瘤的发生发展与肿瘤微环境密切相关。在多种治疗肿瘤的研究方法中,微环境疗法近年来受到学者们的广泛关注,加快了癌症治疗新方法研究的步伐。现以肿瘤微环境中的关键分子为靶点,对肿瘤的微环境治疗进行综述。主要阐述与肿瘤基质相关的微环境疗法和与炎症关联性癌症的微环境疗法,同时结合部分实验案例进行分析,为采用新方法治疗肿瘤提供了理论基础。The occurrence and development of tumor are closely related with tumor microenvironment.With a variety of research methods,the microenvironment treatment of cancer has been widely studied by researchers in recent years.The pace of new method development for cancer treatment will be accelerated.This paper reviews the key molecules in tumor micro-environment as the targets for the treatment of tumor,mainly elaborating the tumor matrix-related micro-environment therapy and the inflammation associated with cancer micro-environment therapy.Combined with some experimental studies,this contributes to a deeper understanding of cancer and provide the theoretical basis for a new approach for the treatment of cancer.

关 键 词：肿瘤 微环境 新疗法 细胞因子 

分 类 号：R730.51[医药卫生—肿瘤]