缺血性卒中与急性高血糖的关系  

Association between Acute Ischemic Stroke and Acute Hyperglycemia

作　　者：褚亮[1,2] 陈艳梅[1] 姚依群[1] 白旭鹏[1,2] 武云涛[1] 曹晶晶[1] 

机构地区：[1]北京军区总医院干一科,北京100700 [2]山西医科大学第二临床医学院,太原030001

出　　处：《医学综述》2010年第12期1902-1903,共2页Medical Recapitulate

摘　　要：目的分析脑梗死急性期血糖水平与梗死程度及急性期病死率的关系。方法选择120例因急性脑梗死入院并经磁共振或CT检查证实梗死灶的住院患者并检查入院后空腹血糖值(FPG)和糖化血红蛋白(HbA1c)。根据FPG和HbA1c分为血糖正常组和高血糖Ⅰ～Ⅲ组,统计四组患者的大面积脑梗死和死亡情况。结果高血糖Ⅰ组和高血糖Ⅲ组与血糖正常组相比较,大面积脑梗死发生率和急性期病死率均较高且差异有统计学意义(P<0.05)。高血糖Ⅱ组与血糖正常组、高血糖Ⅲ组与高血糖Ⅰ组以及高血糖Ⅲ组与高血糖Ⅱ组相比较,虽然未达到统计学差异但前者均比后者大面积脑梗死发生率和急性期病死率高。结论在急性脑梗死患者中,糖化血红蛋白和空腹血糖值可以反映急性期血糖水平,从而预测患者脑梗死程度和存活情况。Objective To observe the relationship between acute hyperglycemia and acute ischemic stroke.Methods The values of fasting plasma glucose（FPG）and glycosylated hemoglobin（HbA1c）were monitored in 120 patientswith acute cerebral infarction confirmed by MRI or CT.According to FPG and HbA1c values,all the patients were divided into normal glucose group,hyperglycemia groupⅠ,hyperglycemia group Ⅱ,hyperglycemia group Ⅲ.Results Compared with normal glucose group,hyperglycemia groupⅠand Ⅲ had more massive cerebral infarction and higher mortality.Conclusion Acute hyperglycemia reflected by the values of glycosylated hemoglobin and fasting plasma glucose could predict the extent of cerebral infarction and survival in patients with acute cerebral infarction.

关 键 词：缺血性卒中 高血糖 病死率 

分 类 号：R743.3[医药卫生—神经病学与精神病学]