儿童多动症与食物特异性IgG关系研究  

Role of food specific IgG in attention deficit/hyperactivity disorder

作　　者：任华丽[1] 王学艳[1] 张曼[1] 

机构地区：[1]北京世纪坛医院,北京100038

出　　处：《山东医药》2010年第24期18-19,共2页Shandong Medical Journal

基　　金：首都医学发展基金联合攻关项目(2007-390)

摘　　要：目的了解食物特异性IgG与儿童多动症(ADHD)之间的关系。方法将30例ADHD患儿随机分为两组,A组予利他林治疗,B组根据食物特异性IgG检测结果行限制饮食。应用多动症评分量表比较治疗5周后症状改善情况。结果 A、B组患儿在治疗后多动症评分均减低(P<0.05),症状改善率分别为(70±13)%和(57±18)%(P>0.05)。A组发生失眠、厌食各1例。结论根据食物特异性IgG检测结果行限制性饮食可明显改善儿童多动症状,提示食物特异性IgG可能参与ADHD发病机制。Objective To evaluate the relationship between food specific IgG（sIgG） and attention deficit/hyperactivity disorder（ADHD）.Methods Thirty cases of ADHD children were randomly divided into ritalin group（14 cases） and sIgG-positive food restriction group（16 cases）.The curative effects were evaluated by clinical ADHD index after 5 weeks＇ treatment.Results ADHD index after treatment was significantly lower than that before in both groups（P0.05）.The rates of symptom improvement were（70±13）% and（57±18）%,respectively（P0.05）.One case complained of insomnia and one case had anorexia in ritalin group.Conclusion Food sIgG may be involved in the pathogenesis of ADHD,food restriction can ameliorate the symptom of ADHD.

关 键 词：儿童多动症 食物特异性IGG 利他林 

分 类 号：R749.94[医药卫生—神经病学与精神病学]