启膈散加减防治放射性食管炎临床观察  

Effect of Modified Qigesan Preventing Radioactive Esophagitis

作　　者：许利纯[1] 邹彩亮 

机构地区：[1]湖南中医药大学第一附属医院,长沙410007 [2]江西省九江市肿瘤医院,九江332100

出　　处：《中国中医急症》2010年第6期929-930,共2页Journal of Emergency in Traditional Chinese Medicine

基　　金：湖南省教育厅课题(No.2007C488)

摘　　要：目的观察启膈散加减防治放射性食管炎的临床疗效。方法将56例放射性食管炎患者随机分为两组,治疗组自放疗开始口服中药汤剂启膈散加减4～7周;对照组放疗时无预防性给药,对发生放射性食管炎的病例采用普鲁卡因、地塞米松、庆大霉素口服4～7周,至症状消失。结果治疗组降低了放射性食管炎的严重程度,推迟了食管炎的发生时间,减少了症状持续时间,保证了治疗的持续进行,且治疗组较对照组有更多患者顺利完成放疗。结论启膈散对放射性食管炎治疗效果显著,既可作为预防用药也可作为治疗用药,宜在临床上推广。Objective： To observe the clinical effect of modified Qigesan preventing radioactive esophagitis. Methods： 56 radioactive esophagitis patients were divided randomly into two groups. In the beginning of the radiotherapy, the treatment group was started to be given the modified Qigesan orally. The control group was used drug without prevention. These administrations, containing procaine, dexamethasone and gentamicin, were given the radioactive esophagitis patients in the control group. 2 groups treatments were continued 4-7 weeks into symptoms disappearance. Results： Not only were reduced the severity degree and postponed the onset time of this disease, but also patients in the treatment group were decreased the duration and kept therapy. Moreover, the treatment group was completed the radiotherapy smoothly compared to the control group. Conclusion： Qigesan is remarkable effect in preventing the radioactive esophagitis. It is not solely suitable for prevention therapy but can also be used in the treating. It could be popularization and application in the clinical treatment.

关 键 词：胸部恶性肿瘤 放射性食管炎 启膈散 

分 类 号：R730.59[医药卫生—肿瘤]