肺重复癌发生机制和诊断预测的研究进展(英文)  

The advancement of predictive diagnosis and molecular mechanism in multiple primary lung cancer

作　　者：袁岚 刘伦旭 车国卫 

机构地区：[1]Department of Cardiovascular Thoracic Surgery,West China Hospital,Sichuan University

出　　处：《Chinese Journal of Cancer》2010年第5期575-578,共4页

摘　　要：Due to the advanced diagnostic technique and better understanding for multiple primary lung cancers(MPLC),the increasing incidence of MPLC has been reported.Very often,MPLC are misdiagnosed as metastasis because of lacking efficient molecular biomarkers for prediction and diagnosis.Studies on the molecular mechanism for tumorgenesis and progression of MPLC may therefore facilitate the discovery of biomarkers for disease diagnosis and prognosis,so that an individual and rational treatment can be achieved.We tried to further our understanding and improve the diagnostic skill for MPLC by reviewing the current status and the latest advancement of molecular markers related to MPLC.Due to the advanced diagnostic technique and better understanding for multiple primary lung cancers（MPLC）,the increasing incidence of MPLC has been reported.Very often,MPLC are misdiagnosed as metastasis because of lacking efficient molecular biomarkers for prediction and diagnosis.Studies on the molecular mechanism for tumorgenesis and progression of MPLC may therefore facilitate the discovery of biomarkers for disease diagnosis and prognosis,so that an individual and rational treatment can be achieved.We tried to further our understanding and improve the diagnostic skill for MPLC by reviewing the current status and the latest advancement of molecular markers related to MPLC.

关 键 词：诊断技术 分子机制 原发性 肺癌 分子标志物 预测 肿瘤发生 预报方法 

分 类 号：R734.2[医药卫生—肿瘤]