老年女性交界性卵巢上皮性肿瘤预后及复发原因分析  

Clinical analysis of prognosis and recurrence of borderline epithelial ovarian tumors in aged women

作　　者：王东红[1] 孙丽君[1] 肖雁冰[1] 安强[1] 王明阳[1] 

机构地区：[1]遵义医学院附属医院妇产科,563003

出　　处：《中华老年医学杂志》2010年第6期489-491,共3页Chinese Journal of Geriatrics

摘　　要：目的 探讨影响老年女性交界性卵巢上皮性肿瘤预后及复发的因素.方法 回顾性分析在我院治疗的老年女性交界性卵巢上皮性肿瘤102例临床资料和随访资料,采用单因素及多因素Logistic回归分析影响预后及复发的相关因素.结果 单因素分析显示,5年生存率与术后辅助治疗、腹膜种植及淋巴结转移有关（χ2值分别19.311、11.054、18.559,均P＜0.01）;手术方式、腹膜种植、淋巴转移及微浸润对复发的影响差异有统计学意义（χ2值分别23.606、23.583、25.774、23.583,均P＜0.01）.多因素Logistic回归分析结果显示,术后辅助治疗（OR=0.060,P＜0.01）、腹膜种植（OR=35.319,P＜0.01）是5年生存率的独立危险因素.手术方式（OR=0.001,P＜0.05）、腹膜种植（OR=60.952,P＜0.05）、微浸润（OR=88.874,P＜0.01）是复发的独立危险因素.结论 早期规范治疗老年女性交界性卵巢上皮性肿瘤可获得良好的预后,但存在复发的风险,应重视腹膜种植、淋巴转移和微浸润患者的随访.Objective To evaluate the effect of clinic-pathological variables on prognosis and recurrence of the aged women suffered from borderline epithelial ovarian tumors. Methods The clinical and follow-up data of 102 cases were analyzed retrospectively. Univariate and multivariate logistic regression analysis were used to assess independent prognosis and recurrence factors.Results The postoperative accessory treatment, peritoneal implantation and lymph nodes metastasis could influence the 5-year survival rate（χ2=19.311, 11.054, 18. 559, all P＜0.01）. The surgery procedure, peritoneal implantation, lymph nodes metastasis and microinvasion could influence the recurrence rate（χ2=23.606, 23.583, 25.774, 23.583, all P＜0.01）. The logistic regression model showed that the postoperative accessory treatment and peritoneal implantation were the two independent prognosis factors （OR=0.060, 35.319, all P＜0.01）. The surgery procedure,peritoneal implantation and microinvasion were the three independent factors affecting recurrence（OR =0.001, P＜0.05;OR=60.952, P＜0.05;OR=88.874, P＜0.01）. Conclusions The early standard treatment on borderline epithelial ovarian tumors of the aged women have an excellent prognosis, the risk of recurrence remains in some patients. We emphasize that these patients with highrisk factors should be main surveillance population.

关 键 词：卵巢 肿瘤种植 淋巴转移 

分 类 号：R737.31[医药卫生—肿瘤]