先天性角化不良1例  

A Case of Dyskeratosis Congenita

作　　者：王杨 汪治国 阮英[2] 

机构地区：[1]湖北省咸宁市中心医院皮肤科,湖北咸宁437100 [2]湖北省咸宁学院皮肤科教研室,湖北咸宁437100

出　　处：《中国皮肤性病学杂志》2010年第6期549-550,共2页The Chinese Journal of Dermatovenereology

摘　　要：患者男,21岁,具有临床三联征:全身皮肤网状色素沉着,甲营养不良和口腔黏膜白斑。并发头发稀少、干枯,有龋齿。腕部皮肤色素沉着区皮损活检示:角化过度、角化不全,基底细胞液化变性,真皮上层较多嗜色素细胞。A case of dyskeratosis congenita （DC） of a 21-year-old male is reported. He presented with the characteristic clinical triad of reticular pigmentation of the skin, dystrophic nails and oral lesions. In addition, sparse and withered hairs and dental caries were accompanied. Skin biopsy specimen from hyperpigmented areas of wrist shows hyperkeratosis, parakeratosis, liquifaction degeneration of basal cells and many melanophages in superficial dermis.

关 键 词：角化不良 先天性 

分 类 号：R758.5[医药卫生—皮肤病学与性病学]