2%氯己定对牙本质自酸蚀粘接强度影响的初步研究  

Effect of 2% chlorhexidine on the bond strength of self-etch adhesive system to human dentin

作　　者：李景辉[1,2] 刘慧[1] 乔佳[1] 张振庭[1] 

机构地区：[1]首都医科大学口腔医学院,北京2007级博士研究生100050 [2]首都医科大学附属北京友谊医院口腔科

出　　处：《北京口腔医学》2010年第3期132-134,共3页Beijing Journal of Stomatology

摘　　要：目的采用微拉伸方法检测基质金属蛋白酶抑制剂(2%氯己定)是否影响牙本质自酸蚀粘接的粘接强度。方法将8颗新鲜拔除的人下颌第三磨牙去除冠部釉质,暴露中层牙本质,随机分成两组,对照组用ClearfilSEBond粘接剂粘接,实验组粘接前用2%氯己定处理粘接面牙本质,硬组织切片机切成1mm×1mm×8mm的微拉伸试件40个,测试两组即刻和水储存6个月时的微拉伸强度,并对断裂样本进行电镜观察。结果对照组和实验组的即刻微拉伸强度分别为40.56±2.78Mpa、41.20±2.66Mpa,两组即刻粘接强度无统计学差异(P>0.05);6个月时微拉伸强度实验组高于对照组(P<0.05)。结论 2%氯己定对牙本质自酸蚀粘接的即刻粘接强度没有影响;经过6个月储存后,能够减缓粘接强度的下降。Objective To evaluate the effect of protease inhibitors（2% chlorhexidine）on micro-tensile bond strength（μTBS）of self-etch adhesive system to human dentin.Methods The occlusal enamal of 8 extracted third molars was removed to expose the flat middle coronal dentin.One half of the specimen was bonded with Clearfil SE Bond adhesive only,and the other treated with 2% chlorhexidine after being bonded.Bonded specimens were tensioned at 0.5 mm/min immediately and 6 months later respectively.Failure mode analysis was performed by scanning electron microscope（SEM）.Results There was no difference in the immediate micro-tensile bond strength between control and experimental group.But after 6 months of water preservation,the micro-tensile bond strength of the experimental group was higher than that of the control（P〈0.05）.Conclusion Chlorhexidine might be useful for the preservation of dentin bond strength.

关 键 词：牙本质粘接 氯己定 自酸蚀 基质金属蛋白酶(MMPs) 

分 类 号：R783.1[医药卫生—口腔医学]