非酒精性脂肪肝肝脾CT值比值与肝功能及血脂关系的分析  

Study of the Relationship Among Liver to Spleen CT Value Ratio,Liver Function and Blood Lipid in Patients with Nonalcoholic Fatty Liver Disease

作　　者：刘珺[1] 叶斌[1] 王维[1] 唐医亚[1] 童琼娟[1] 

机构地区：[1]中南大学湘雅三医院放射科,长沙410013

出　　处：《临床放射学杂志》2010年第6期769-771,共3页Journal of Clinical Radiology

摘　　要：目的探讨非酒精性脂肪肝(nonalcoholic fatty liver disease,NAFLD)患者肝脾CT值比值与肝功能及血脂的关系。资料与方法对132例NAFLD患者分别行CT平扫、肝功能及血脂检测,然后根据肝功能及血脂有无异常进行分组。结果 132例NAFLD患者,肝功能正常54例,肝功能异常78例;血脂正常45例,血脂异常87例。肝功能正常组与异常组其肝脾CT值比值有差异;血脂正常组与异常组其肝脾CT值比值亦有差异;肝脾CT值比值与甘油三酯(TG)、总胆固醇(CHOL)、低密度脂蛋白(LDL)、极低密度脂蛋白(VLDL)呈明显负相关(P<0.01),与高密度脂蛋白(HDL)呈正相关(P<0.01);而与丙氨酸氨基转氨酶(ALT)、天冬氨酸氨基转氨酶(AST)无相关性(P>0.05)。结论 NAFLD肝脾CT值比值与血脂密切相关,而与肝功能氨基转氨酶的变化无明显相关性。Objective To explore the relations among liver to spleen CT values ratio,liver function and blood lipid in patients with nonalcoholic fatty liver disease（NAFLD）.Materials and Methods 132 patients having nonalcoholic fatty liver disease were performed conventional CT scanning,liver function and blood lipid tests,and then categorized them based on the results of liver function and blood fat exams,respectively.Results Among 132 patients included,54 of them had normal liver function,78 had abnormal liver function,while 45 cases with ortholiposis and 87 with dyslipidemia.There were differences in liver to spleen CT values ratio between the groups with and without normal liver function,and the groups with and without ortholiposis as well.Liver to spleen CT values ratio,in addition,had significant negative correlation with TG、CHOL、LDL、VLDL（P〈0.01）and positive correlation with HDL（P〈0.01）.However,as to ALT and AST,there were no correlation among them（P〉0.05）.Conclusion In NAFLD patients,liver to spleen CT values ratio is closely related to blood lipid,but not to liver function.

关 键 词：非酒精性脂肪肝 体层摄影术 X线计算机 肝功能 血脂 比值 

分 类 号：R575.5[医药卫生—消化系统]