胃食管阀瓣与反流性食管炎的关系初步探讨  

Relationship between gastroesophageal flap valve and reflux esophagitis

作　　者：胡景[1] 

机构地区：[1]首都医科大学附属复兴医院消化科,北京100038

出　　处：《中华消化内镜杂志》2010年第6期291-294,共4页Chinese Journal of Digestive Endoscopy

摘　　要：目的 探讨胃食管阀瓣（GEFV）与反流性食管炎（RE）的关系.方法 分析2007年1月至2009年12月我院内镜诊断的BE 239例,按洛杉矶标准进行食管炎分级,按Hill分类法进行GEFV的分级.通过对照分析,探讨GEFV与RE之间的关系.结果 入组的960人中,异常GEFV发生率32.9%,RE发生率24.9%.重症RE（C级、D级）发生率GEFV异常组明显高于GEFV正常组（23.1%比2.4%,P=0.000）;RE分级与GEFV级别呈正相关（r=0.308,P=0.000）.RE患者的异常GEFV发生率高于非食管炎者（65.3%比22.2%,P=0.000）.RE患者和异常GEFV组均为男性多于女性（63.6%、60.1%比36.4%、39.9%,P=0.000）.各年龄段中,随着年龄的增长,RE巳的发生率逐渐升高,年龄增长与RE发生率呈正相关,（r=0.214,P=0.000）.30岁以上,随着年龄的增长,异常GEFV的发生率逐渐升高,年龄增长与异常GEFV的发生率呈正相关（r=0.129,P=0.000）.结论 GEFV异常和RE发生存在相关性,观察GEFV可作为评估和预测患者反流状态的有效方法.Objective To investigate the relationship between gastroesophageal flap valve （GEFV） and reflux esophagitis（RE）.Methods We analyzed 239 cases of RE diagnosed by endoscopy in our hospital from January 2007 to December 2009.RE was classified by Los Angeles classification system and GEFV by Hill system.The association of GEFV with RE was analyzed.Results The overall incidence of abnormal GEFV was32.9% （316/960） and that of RE was 24.9% （239/960）.The incidence of severe RE （ grade C and D） in abnormal GEFV group was significantly higher than that in normal GEFV group （23.1% vs.2.4% , P = 0.000）.RE grades were positively correlated with GEFV grades （r = 0.308, P = 0.000 ）.The incidence of abnormal GEFV in RE patients was higher than that in non-RE （65.3% vs.22.2% ,P = 0.00 ）.In terms of gender, there were more males than females in both RE group （63.6% vs.36.4% ） and abnormal GEFV group （60.1% vs.39.9% ）.Additionally, incidence of RE increased with age, i.e.positively correlated with age （r=0.214,P =0.000）.The incidence of abnormal GEFV also increased significantly in those over 30 years old, i.e.positively correlated （ r = 0.129, P = 0.000）.Conclusion There is correlation between GEFV abnormality and RE.GEFV provides useful information for assessment and prediction of the reflux status of the patients.

关 键 词：食管炎 反流性 胃食管阀瓣 影响因素 

分 类 号：R571[医药卫生—消化系统]