^(18)F-脱氧葡萄糖PET对非恶性肿瘤摄取的分析与识别  

Analysis and Identification of ^(18)F-FDG Uptake in the PET Studies of Non-malignant Tumors

作　　者：杨星[1] 任庆余[1] 张林[1] 

机构地区：[1]解放军白求恩国际和平医院核医学科,石家庄050082

出　　处：《临床误诊误治》2010年第6期567-569,共3页Clinical Misdiagnosis & Mistherapy

摘　　要：目的探讨PET表现特殊的非肿瘤性异常放射性摄取的原因,提出鉴别诊断方法。方法对2004年8月～2008年8月18F-脱氧葡萄糖(18F-FDG)PET全身显像表现为局部明显异常放射性摄取,经病理或临床随访证实为非恶性肿瘤98例的PET、CT图像进行综合分析,总结鉴别诊断要点。结果本组PET图像均显示有明显异常的局限性放射性摄取,绝大多数浓聚灶标准化摄取值(SUV)最大值超过2.5,其中2例曾误诊为恶性肿瘤。98例中证实为感染与炎症病变46例,生理性摄取28例,良性病变24例。结论在18F-FDGPET全身显像中,非恶性病变放射性摄取在PET、CT图像以及临床上各有特点,易误诊,应予以高度重视。Objective To analyze significant radioactive uptakes of 18F-FDG in the PET studies of common non-malignant tumors,and suggest methods of differential diagnosis.Methods 98 non-malignant cases with radioactive local uptakes of ^18F-FDG were collected（Aug.2004～Aug.2008）,which were subsequently confirmed by pathological results and clinical follow-ups;then analysis of their PET images and CT images were performed in combination with clinical features,and the main points of differential diagnosis were summarized.Results PET images showed that there was obvious abnormal local radioactive uptakes and most of the SUV was over 2.5 in maximum.Of the 98 patients,there were 24 cases of benign lesions,46 cases of infection and inflammation,28 cases of physiologic uptakes;obvious abnormal local uptakes were found in all of the 98 patients;among whom,two cases were misdiagnosed as malignant.Conclusion In ^^18F-FDG PET whole body imaging for radioactive uptakes of ^18F-FDG in non-malignant lesions,there are separately different characteristics in their PET images,CT images and clinical aspects;they often tend to be misdiagnosed,and thus special attention should be paid to such cases.

关 键 词：正电子发射断层显像术 肺疾病 纵隔疾病 淋巴结炎 结核 肺 诊断 鉴别 

分 类 号：R730.4[医药卫生—肿瘤]