中国武安市食管癌高发区胃镜普查初步研究  

Endoscopic Screening for Esophageal Cancer in Wu'an City

作　　者：李鹏[1] 张澍田[1] 王拥军[1] 吕富靖[1] 李巍[1] 王青釭[1] 赵海英[1] 刘萱[1] 宗晔[1] 周巧直[1] 焦月[1] 郝建宇[2] 冀明[1] 吴咏冬[1] 于中麟[1] 

机构地区：[1]首都医科大学附属北京友谊医院消化内科北京市消化疾病中心 [2]首都医科大学附属北京朝阳医院消化内科

出　　处：《首都医科大学学报》2010年第3期339-342,共4页Journal of Capital Medical University

基　　金：国家高技术研究发展计划(863计划)(2007AA02Z4Z4)资助项目~~

摘　　要：目的在河北省武安市食管癌高发区建立普查基地,在大规模食管癌普查工作前,先进行预试验研究。方法对武安市上团城乡上团城村一街的居民进行逐个入户调查,对年龄40～65岁的居民登记,进行问卷调查;获取知情同意后,进行胃镜检查,筛查食管癌和癌前病变。结果共对92名居民进行了问卷调查,对88名居民进行了消化内镜检查。19例居民普通内镜或者色素内镜怀疑食管癌或癌前病变者进行内镜下活检,并送病理检查。发现7例为轻-中度异型增生,2例为高度异型增生/原位癌,1例为进展期癌,异型增生及癌变者碘染色不染或者淡染。结论本研究在食管癌高发区进行胃镜普查早期发现食管癌和癌前病变的可行性,为以后长期的研究摸索经验。Objective To establish an esophageal cancer high incidence screening area in Wu＇an City,Hebei Province,a pilot study was carried out before large-scale endoscopic screening. Methods Home by home survey was launched in Shangtuancheng village,Shangtuancheng Town,Wu＇an city,and 40~65 year-old residents were registered to conduct a questionnaire survey. After obtaining informed consent,endoscopy for esophageal cancer and precancerous lesions was performed. Results Among 92 residents who had been surveyed,88 accepted endoscopy,19 residents were suspected of having esophageal cancer and precancerous lesions were biopsied,and sent to department of pathology; 7 cases of low or moderate dysplasia,2 cases of high-grade dysplasia/carcinoma in situ,and 1 case of advanced esophageal cancer were confirmed pathologically. Conclusion This study confirmed the feasibility of esophageal cancer screening in high incidence area,which helps accumulate experience for the future long-term research.

关 键 词：食管癌 癌前病变 胃镜检查 高发区 

分 类 号：R735.1[医药卫生—肿瘤]