不饱和螺环原酸酯与牙科树脂基质的化学固化反应的研究  

Study of Chemical-cured Copolymerization of Unsaturated Spiro Orthoesters and Dental Resin

作　　者：贾芳[1] 付静[1] 张杰魁[1] 邱静[2] 刘小青[1] 

机构地区：[1]四川大学华西口腔医学院口腔材料学教研室,四川成都610041 [2]四川口腔疾病研究国家重点实验室

出　　处：《口腔医学研究》2010年第3期316-319,共4页Journal of Oral Science Research

基　　金：国家自然科学基金资助项目(编号:50673065)

摘　　要：目的:研究一种不饱和螺环原酸酯与牙科树脂基质在室温化学固化条件下的引发体系、聚合性体积收缩率、聚合转化率、开环反应率以及固化时间。方法:MTOSN膨胀单体与Bis-GMA或BisS-GMA树脂基质单体混合后,加入过氧化苯甲酰(BPO)或过氧化二叔丁基(DTBP)热分解型引发剂进行热固化反应;加入由BPO或DTBP引发剂和N,N-二羟丙基对甲苯胺(DHPT)、N,N-二甲基对甲苯胺(DMT)、对甲苯亚磺酸钠(TSS)促进剂进行室温化学固化反应。用红外光谱仪以内标法测试固化物的聚合转化率和开环反应率,用示差热量扫描仪测定固化时间,用膨胀计法测试聚合性体积收缩率。结果:在本实验条件下,BisS-GMA实验组的性能均优于Bis-GMA实验组。DTBP只能做热分解型引发剂,不能做氧化还原引发剂。BPO∶DHPT=1∶1时,MTOSN/BisS-GMA组有较高的聚合转化率与开环反应率,有较低的体积收缩率和固化时间。加入TSS后,能明显降低开环反应率和固化时间。加入MTOSN膨胀单体,能明显降低体积收缩率。结论:当BPO∶DHPT=1∶1时,MTOSN膨胀单体和BisS-GMA树脂基质能发生室温化学固化反应,有较低的体积收缩率,可以作为新型口腔复合树脂的基体树脂。Objective：To investigate the initiating system,the volume shrinkage during copolymerization,the degree of conversion（DC）,the percentage of ring-open and the curing time of unsaturated spiro orthoesters and dental resin in chemical-cured reaction.Methods：2-methylene-1,4,6-trispiro nonane（MTOSN）and Bis-GMA/BisS-GMA were mixed up in the presence of BPO or DTBP as initiator in thermal-cured reaction,and with BPO or DTBP as initiator and DHPT,DMT and TSS as accelerators in chemical-cured reaction.The FT-IR was used to measure the degree of conversion and the percentage of ring-open.DSC was utilized to measure the curing time.Dilatometer was applied to measure the volume shrinkage.Results：Under reactive condition,BisS-GMA performed better than Bis-GMA.Under chemical-cured condition,when ratio of BPO and DHPT was 1：1,BisS-GMA and MTOSN attained high conversion rate,highest percentage of ring-open,moderate curing time and low percentage of volume shrinkage.DTBP could not start chemical-cured reaction at ambient temperature.TSS decreased MTOSN＇s ring-open percentage.Conclusion：In chemical-cured reaction,when ratio of BPO and DHPT was 1：1,BisS-GMA and MTOSN could achieve low percentage of volume shrinkage,which could be the novel kind of dental resin matrix.

关 键 词：不饱和螺环原酸酯 牙科树脂基质 化学固化 体积收缩 

分 类 号：R783.1[医药卫生—口腔医学]