女性精神分裂症患者的性生活质量及相关因素  

Sexual quality of life and related factors in women with schizophrenia

作　　者：胡蕾[1] 胡佩诚[2] 唐茂芹[1] 杨晓东[1] 王爱荣[3] 刘英 曹秉玉[1] 刘兰芬[1] 白录东[1] 朱纬国 

机构地区：[1]山东省精神卫生中心,济南250014 [2]北京大学医学部医学心理教研室,北京10091 [3]济宁市精神病防治院,山东济宁272051 [4]菏泽市第三人民医院,山东菏泽274000

出　　处：《中国心理卫生杂志》2010年第6期430-434,462,共6页Chinese Mental Health Journal

基　　金：国家"985工程"二期(985-2-027-39)

摘　　要：目的:从性满意度、性交流、性焦虑、性反应、性态度、性体像6个方面以及整体状况探讨女性精神分裂症患者的性生活质量及其相关因素。方法:以3所医院门诊就诊的符合CCMD-3精神分裂症诊断标准的女性精神分裂症患者180名作为研究组,按照年龄(±2岁)、城市所在地与精神分裂症组匹配,选择正常女性180名作为对照组,用女性性生活质量问卷,Olson婚姻质量问卷中的夫妻交流、婚姻满意度、性生活3个分量表进行测查。结果:除性焦虑因子外,患者性生活质量总分及其余各个因子分均低于正常对照组[如,性满意度因子,(20.8±4.4)vs.(25.1±4.8),P<0.001]。多元逐步回归分析显示,提高患者总的性生活质量的因素依次为婚姻满意度高、有子女、使用非典型抗精神病药物(β=0.514,0.258,0.193,均P<0.05);提高性满意度的因素按照作用大小依次为婚姻满意度高、使用非典型抗精神病药物(β=0.577,0.225,均P<0.05);改善患者性交流的因素依次为受教育程度高、病程短、有子女(β=0.462,-0.351,0.298,均P<0.05);改善患者性焦虑的因素依次为婚姻满意度高、年龄低(β=0.458,-0.206,均P<0.001);提高患者性反应的因素依次为月经济收入高、病程短、使用非典型抗精神病药物(β=0.457,-0.200,0.158,均P<0.05);改善患者性态度的因素依次为受教育程度高、疾病严重程度轻、夫妻交流多(β=0.469,-0.445,0.271,均P<0.05);对患者性体像有利的因素依次为使用非典型抗精神病药物、婚姻满意度高、无子女(β=0.776,0.415,-0.196,均P<0.05)。结论:促进患者婚姻家庭的和谐,选用对性功能影响小的非典型抗精神病药物维持治疗,可以提高患者的治疗依从性,使患者的性生活质量得到改善。Objective： To explore the sexual quality of life and related factors in women with schizophrenia. Methods： A total of 180 female outpatients who met diagnostic criteria of CCMD-3 （ Chinese Classification and Diagnostic Criteria for Mental Disorders, the 3rd edition） for schizophrenia were recruited from 3 hospitals, and 180 healthy women matched for age （ ±2 years） and residential location were adopted as a control group. All subjects were assessed with the Sexual Quality of Life Questionnaire for Women and 3 subscales of theENRICH Marital Inventory （ communication, marital satisfaction and sexual relationship ） . Results： Except for the score of sexual anxiety, the total score and the other sub-scores in patients were lower than that in normal controls [ e. g. , sexual satisfaction, { 20. 8 ± 4. 4 } vs. （ 25. 1 ± 4. 8 ）, P 〈 0. 001 ] . Multiple stepwise regression showed that factors improving sexual quality of life in the whole state in women with schizophrenia were high marital satisfaction, having children and atypical antipsychotics in turn （β =0.514, 0.258 and 0. 193, Ps 〈0.05} . The improvement of sexual satisfaction was related to high marital satisfaction and atypical antipsychotics （ β = 0. 577, 0. 225, Ps 〈0. 05} . Factors improving sexual communication were high education, short illness duration and having children （ β = 0. 462, - 0. 351 and 0. 298, Ps 〈 0. 05 ） . Factors relieving sexual anxiety were high marital sat- isfaction and young age {β =0. 458, -0. 206, Ps 〈0. 001 ） . Factors improving sexual response were high monthly income, short illness duration and atypical antipsychotics （ β = 0. 457, - 0. 200 and 0. 158, Ps 〈 0. 05 } . Opening sexual attitude corelated with high education, mild clinical symptoms and well communication （ β = 0. 469, -0. 445and 0. 271, Ps 〈0. 05 ） . Factors being beneficial to sexual image were atypical antipsychotics, high marital satisfaction and no children （ β = 0. 776, 0. 415 and - 0. 196, Ps 〈 0. 05

关 键 词：女性 精神分裂症 性生活质量 横断面研究 

分 类 号：R749.3[医药卫生—神经病学与精神病学] C913.14[医药卫生—临床医学]