中国儿童乳糖不耐受发生率的调查研究  

Study on the incidence of lactose intolerance of children in China

作　　者：杨月欣[1,2,3,4] 何梅[1,2,3,4] 崔红梅 边丽华[1,2,3,4] 刘建宇 程五凤[1,2,3,4] 徐浩烽 丰维佳[1,2,3,4] 

机构地区：[1]中国预防医学科学院营养与食品卫生研究所 [2]上海第二医学院 [3]广东省卫生防疫站学校卫生科 [4]哈尔滨市南岗区卫生防疫站

出　　处：《卫生研究》1999年第1期44-46,共3页Journal of Hygiene Research

基　　金：新加坡亚太区达能科研基金

摘　　要：随机选择北京、上海、广州和哈尔滨４大城市的３～１３岁健康儿童１１６８名，采用乳制品摄入量频率调查、乳糖耐量试验和氢呼气试验的方法，研究了中国儿童乳糖酶缺乏和乳糖不耐受的发生率。结果表明：３～５岁，７～８岁和１１～１３岁组儿童中，乳糖酶缺乏的发生率分别为３８．５％、８７．６％和８７．８％。乳糖不耐受发生率分别为１２．２％、３２．２％和２９．０％。中国４大城市儿童乳糖酶降低或消失发生的年龄在７～８岁。当儿童食用５０ｇ奶粉（含１３～１４ｇ乳糖）时，吸收不良和不耐受的发生率显著下降，但学龄儿童中仍有３９％～４１．７％为吸收不良、牛奶不耐受症状发生率１４％～１６．７％。研究未发现乳糖酶缺乏的发生和儿童的喂养史。healthy children of 3～13 years old were selected as subjects from Beijing, Shanghai, Guangzhou and Haerbin. Total subjects were challenged by 25 gram lactose test. The breath hydrogen was determined, the symptoms of lactose intolerance were recorded. The results showed that the incidences of lactase deficiency of children of 3～5, 7～8 and 11～13 years old were 38 5%, 87 6% and 87 8% respectively. The incidences of lactose intolerance were 12 3%, 33 2% and 30 5% respectively. Lactase activity decreasing of Chinese children occured at the age of 7～8 years old, and the symptom of lactose intolerance depended on lactose dose. But, there still are 39%～41 7% chil

关 键 词：儿童 牛奶 乳糖酶缺乏 乳糖不耐受 

分 类 号：R153.2[医药卫生—营养与食品卫生学] R151.42[医药卫生—公共卫生与预防医学]