瘦素在恶性腹水和结核性腹水的表达  

The expression of leptin in patients with malignant and tuberculous ascites

作　　者：李曦[1] 施炳龙[1] 

机构地区：[1]北京大学深圳医院消化内科,51836

出　　处：《中国实用医药》2010年第18期4-5,共2页China Practical Medicine

基　　金：深圳市科技计划项目(项目编号:200803029)

摘　　要：目的探讨瘦素在恶性,结核性腹水患者中的表达的意义。方法笔者分析了结核性腹水患者15例,恶性腹水患者30例。这些患者采用ELISA法测定腹水,血清瘦素水平。结果结核性腹水患者血清,腹水中瘦素水平高于恶性腹水患者,有统计学意义。(P<0.05)。结核性腹水,恶性腹水患者腹水中瘦素水平高于血清中水平。结论瘦素水平的检测可能有助于结核性腹水和恶性肿瘤性腹水患者的诊断。Objective To investigate the value of leptin in patients with malignant and tuberculous as- cites. Methods Leptin in blood serum and ascites were measured by ELISA method. The patients with tubercu- lous （15 eases） and malignant ascites （30 cases） were included. Results leptin levels in patients with tuber- culous aseite was higher than those in malignant ascites. The ascites leptin level in patients with tuberculous as- eites was higher than serum leptin level. Conclusion The measurement of ascites or serum leptin level may be useful for differential diagnosis of benign or malignant aseites.

关 键 词：结核性腹水 恶性腹水 瘦素 

分 类 号：R730.4[医药卫生—肿瘤]