急性一过性核间性眼肌麻痹临床分析  

Clinical analysis of acute a transient internuclear ophthalmoplegia

作　　者：张建华[1] 陈文武[2] 方亚非[1] 石荣先[1] 李彬[1] 

机构地区：[1]河南大学第一附属医院眼科,河南省开封475001 [2]河南大学第一附属医院神经内科,河南省开封475001

出　　处：《临床眼科杂志》2010年第3期254-256,共3页Journal of Clinical Ophthalmology

摘　　要：目的探讨急性一过性核间性眼肌麻痹的发病机制及预防措施。方法对急性一过性核间性眼肌麻痹患者的临床资料进行回顾性分析和总结。8例患者中男6例,女2例;年龄最大76岁,最小54岁,平均63.7岁。临床上突然出现复视,伴有头晕、恶心;诊为前核间性右眼内直肌麻痹5例,前核间性左眼内直肌麻痹3例。结果所有患者在发病后8～19h,平均14.3h内完全恢复,无任何并发症和后遗症发生。结论急性一过性核间性眼肌麻痹是由于一过性内侧纵束局部血液供应障碍,或者是脑供血不足的局部表现所致。积极治疗脑供血不足可以有效的预防本病的发生。Objective To investigate the acute transient internuclear ophthalmoplegia in the pathogenesis and preventive measures.Methods The acute transient internuclear ophthalmoplegia in patients with clinical data were retrospectively analyzed and summarized.8 patients in 6 male and 2 females;the oldest 76 years old,minimum 54-year-old,with an average 63.7 years old;clinical sudden diplopia,accompanied by dizziness,nausea;diagnosed as former nuclear inter-right eye medial rectus paralysis in 5 cases,the former nuclear inter-medial rectus paralysis of his left eye in 3 cases.Results All patients after the onset of 5~18 hours,an average of 10.3 hours less than full recovery without any complications and sequelae.Conclusion Acute transient internuclear ophthalmoplegia is due to a transient local blood supply to the medial longitudinal fasciculus barrier,or partial performance of the brain due to insufficient blood supply.Active treatment of cerebral insufficiency can effectively prevent the occurrence of this disease.

关 键 词：核间性 眼外肌麻痹 一过性脑缺血 

分 类 号：R777.45[医药卫生—眼科]