新疆Kaposi肉瘤与皮肤鳞状细胞癌感染HHV-8阳性率的比较研究  

Comparative study of the positivity rate of HHV-8 infection in KS and SCC of skin

作　　者：李振飞[1] 普雄明[2] 

机构地区：[1]新疆医科大学 [2]新疆维吾尔自治区人民医院皮肤性病科,新疆乌鲁木齐830000

出　　处：《新疆医科大学学报》2010年第5期523-525,共3页Journal of Xinjiang Medical University

基　　金：新疆维吾尔自治区自然科学基金项目(2009211A24)

摘　　要：目的探讨Kaposi肉瘤与皮肤鳞状细胞癌(SCC)感染人类疱疹病毒8型(HHV-8)的差异。方法用巢式PCR分别扩增30例鳞状细胞癌和30例Kaposi肉瘤组织皮损中的HHV-8 DNA。结果 30例皮肤鳞状细胞癌皮损组织有5份为阳性(16.7%),30例Kaposi肉瘤组织有28份为阳性(93.3%)。结论鳞状细胞癌感染HHV-8的阳性率较低,但并不除外HHV-8为新疆皮肤鳞状细胞癌的病因之一。Objective To investigate the different rate of Herpes vinrus hominis-8（HHV-8） infection between kaposi sarcoma（KS） and skin squamous-celled carcinoma（SCC）.Methods Thirty specimens of SCC of skin and Thirty specimens of KS were collected to detect HHV-8 expression by nesting PCR.Results The positivity rate of HHV-8 infection in SCC of skin was 16.7%（5/30）,while that in KS was 93.3%（28/30）.Conclusion There was lower HHV-8 infection rate in skin SCC,but that may be the cause of skin SCC in Xinjiang.

关 键 词：人疱疹病毒8型 鳞状细胞癌 KAPOSI肉瘤 ORF26 

分 类 号：R730.269[医药卫生—肿瘤] R739.5[医药卫生—临床医学]