四种手术方法治疗翼状胬肉168眼  

Four surgical treatments of pterygium on 168 eyes

作　　者：王玉霞[1] 肖瑛[1] 孙洪义[1] 高雪[1] 刘景[1] 陈国玲[1] 杨丽霞[1] 

机构地区：[1]山东大学第二医院眼科,济南250033

出　　处：《山东大学耳鼻喉眼学报》2010年第3期64-66,共3页Journal of Otolaryngology and Ophthalmology of Shandong University

摘　　要：目的探讨单纯翼状胬肉切除术、翼状胬肉切除联合丝裂霉素C、翼状胬肉切除联合带角膜缘的结膜瓣移植术、翼状胬肉切除联合羊膜移植术四种方法治疗胬肉的手术效果。方法分析翼状胬肉患者158例（168眼）接受不同手术方式的手术效果。其中,A组（41眼）接受单纯翼状胬肉切除术,B组（42眼）接受单纯胬肉切除联合丝裂霉素C术,C组（44眼）接受翼状胬肉切除联合带角膜缘的结膜瓣移植术,D组（41眼）接受翼状胬肉切除联合羊膜移植术。术后随访6~12个月。结果 A组复发率17.1%,B组复发率为9.5%,C组复发率4.5%,D组复发率为4.9%。A组的复发率和其它三组比较差异有统计学意义（P（0.05）;B、C组、B、D组、C、D组复发率的比较差异无统计学意义（P（0.05）。C组的并发症较其他三组的并发症少。结论翼状胬肉切除联合带角膜缘的结膜瓣移植术是目前值得推广的手术方式,具有经济实用、复发率低、角膜上皮愈合快、并发症少等优点。Objective To compare the therapeutic effects of simple pterygium excision,pterygium excision combined with mitomycin C,limbus corneae stem cell transplantation,or amniotic membrane transportation on pterygium.Methods 168 eyes of 158 patients were divided into four groups,i.e.groups A,B,C and D,in terms of applied treatments.41 eyes（group A）,42 eyes（group B）,44 eyes（group C） and 41 eyes（group D） were treated with simple pterygium excision,pterygium excision combined with mitomycin C,limbus corneae stem cell transplantation,or amniotic membrane transportation,respectively.The patients were followed up from 6 months to one year.Results The recurrence rates of pterygium in groups A,B,C and D were 17.1%,9.5%,4.5% and 4.9%,respectively.The difference between group A and the other three groups（B,C and D）was statistically significant（P0.05）,whereas there was no statistical significance between groups B C,groups B D and groups C D.Group C had fewer complications than the other three groups.Conclusion Pterygium excision combined with limbus corneae stem cell transplantation is the preferable methods while it demonstrates better cost-effectiveness,lower recurrence rate,shorter corneal epithelial healing time and fewer complications.

关 键 词：翼状胬肉 丝裂霉素C 带角膜缘的结膜瓣移植 羊膜移植 

分 类 号：R777.33[医药卫生—眼科]