SPECT/CT符合线路显像对肺腺癌摄取^(18)F-FDG影响因素的研究  

The study of the influence on ^(18)F-fluorodeoxyglucose(^(18)F-FDG) uptaking of adenocarcinoma of lung by SPECT/CT CoDe imaging

作　　者：陆武[1] 杨成喜[2] 刘永[1] 宋长祥[1] 经丰琴[1] 吴爱玲[1] 吉桂萍[1] 

机构地区：[1]江苏省连云港市第一人民医院核医学科,江苏连云港222002 [2]江苏省连云港市第一人民医院肿瘤科,江苏连云港222002

出　　处：《医学影像学杂志》2010年第6期820-822,共3页Journal of Medical Imaging

摘　　要：目的:应用SPECT/CT符合线路显像半定量分析,探讨肺腺癌摄取18F-FDG的影响因素。方法:31例肺腺癌患者行SPECT/CT检查,计算肿瘤组织与周围正常软组织(T/N)的摄取比值,分析性别、病灶大小、肿瘤细胞分化程度等因素与肺腺癌摄取18F-FDG的相关性。结果:肿瘤病灶大小、癌细胞的分化程度对肺腺癌摄取18F-FDG的影响有显著性意义(P<0.05);性别对肺腺癌摄取18F-FDG的影响无显著性意义。结论:肺腺癌对18F-FDG摄取与肿瘤病灶大小、癌细胞的分化程度有关,与性别无关,18F-FDG摄取值高提示病灶的恶性程度高。Objective：To investigate the influence on the 18-fluorodeoxyglucose（^18F-FDG） uptaking of adenocarcinoma of lung by SPECT/CT CoDe imaging.Methods：Thirty-one cases with adenocarcinoma of lung were checked by SPECT/CT and the ratio of T/N was calculated.We related the influence of gender, the size of tumer and the degree of cell differentiation on the ^18F-FDG uptaking in adenocarcinoma of lung.Results：The influence of the size of tumer and the degree of cell differentiation on the 18 F-FDG uptaking value in adenocarcinoma of lung was great significant（P0.05）.Gender had little influence on the ^18F-FDG uptaking value.Conclusion：The size of lesions and the degree of cell differentiation are correlated to the ^18F-FDG uptaking value in adenocarcinoma of lung patients.The higher ^18F-FDG uptaking value indicates the worse malignancy.

关 键 词：肺腺癌 单光子发射计算机断层成像 18-氟脱氧葡萄糖 

分 类 号：R734.2[医药卫生—肿瘤] R814.42[医药卫生—临床医学]