32例结直肠锯齿状腺瘤的内镜表现及病理学特征分析  

Endoscopic and Histopathological Features of Serrated Adenoma of Large Intestine:an Analysis of 32 Cases

作　　者：贾兴芳[1] 刘成霞[1] 牛琼[1] 史宁[1] 穆琳[1] 陈学芝[1] 

机构地区：[1]滨州医学院附属院医院消化内科,滨州256603

出　　处：《临床消化病杂志》2010年第3期147-149,161,共4页Chinese Journal of Clinical Gastroenterology

基　　金：山东省教育厅科技计划项目(J06L52)

摘　　要：目的探讨结直肠锯齿状腺瘤(SA)的内镜下形态和病理学特征。方法收集并分析1996年1月至2008年5月我院检出的32例SA的内镜和病理资料。结果 32例患者共检出SA60枚,其中35枚为隆起型(无蒂23枚,亚蒂7枚,有蒂5枚),25枚为扁平型。SA常见于乙状结肠及直肠(乙状结肠29枚,直肠11枚)。组织病理学上,管状、管状绒毛状和绒毛状SA分别为41枚、9枚、10枚;不典型增生程度,轻度48枚,中度7枚,重度5枚,其中4枚局部癌变。大于或等于10mmSA较10mm以下的SA不典型增生程度重(P<0.01)。结论大于或等于10mm的SA较10mm以下的SA更易癌变,应引起临床及内镜工作者的重视。Objective To explore the endoscopic and histopathological morphology of colorectal serrated adenomas（SA）. Methods The endoscopic and pathological of 32 SA patients, diagnosed in the affiliated hospital of Binzhou medical college from January 1996 to May 2008, were analyzed respectively. Results 35 of the 60 serrated adenomas were protruded （ sessile 23, semipedunculated 7, pedunculated 5 ） and 22 were platode. SA were frequently located in the sigmiod and rectumcsigmoid 29 and rectum 11 ）. Histopathologically, SA contained tubular glands in 41, tubulovillous glands in 9 and villous glands in 10. Mild dysplasia was found in 48, moderate dysplasia in 7,and sevee dysplasia in 5, cancertion foei in 4. The dysplasia of SA≥10 mm was significantly worse than that of SA 〈 10 mm （ P 〈 0.05 ）. Conclusion The SA≥ 10 mm was easier to carcinomatous change than SA 〈 10 min. SA should arouse clinical and endoscopic workers attention.

关 键 词：锯齿状腺瘤 临床 结肠镜检查 病理学 

分 类 号：R735.3[医药卫生—肿瘤]