帕病2号方治疗震颤型帕金森病的临床研究  

Clinical research of tremor type parkinson's disease with PD NO.2

作　　者：范宇鹏[1] 曾亮[1] 孙玉芝[1] 苏巧珍[1] 连新福[1] 

机构地区：[1]广东省中医院神经内科,广州510120

出　　处：《天津中医药》2010年第3期190-191,共2页Tianjin Journal of Traditional Chinese Medicine

基　　金：广东省中医药管理局项目(2009388)

摘　　要：[目的]初步评价以乌梅丸加减的帕病2号方治疗震颤型帕金森病的临床疗效。[方法]采用前瞻性的随机对照试验,对本院帕金森病专科门诊和病房60例合格受试者,用简单随机法按1:1比例随机分配至治疗组和对照组,其中治疗组30例,对照组30例,治疗组采用中西医结合疗法,给予帕病2号汤剂口服,1剂/d,配合西药美多巴片,对照组只口服美多巴,观察周期3个月。[结果]治疗组治疗震颤型帕金森病在改善患者精神、行为和情绪、日常活动、运动功能方面有效,与对照组比较有统计学意义(P<0.05)。[结论]震颤型帕金森病从肝肾论治,以肝肾亏虚,肝风内动为基本病机,给予滋养肝肾,熄风止颤法治疗,可取得一定的临床疗效。[Objection] To make a clinical research for preliminarily evaluation to the clinical efficacy of PD NO.2 from WuMei pill on Parkinson＇s Disease.[Methods] This research was a prospective randomized controlled trial.All the sixty qualified patients came from PD special out-patient or hospital patients of Guandong Hospital of Traditional Chinese Medicine.These patients were randomly divided into two groups：thirty in the treatment group,thirty in the control group.The therapy of the treatment group was：Decoction of PD NO.2,PO,once a day,together with Madopar,PO,three times a day.The therapy of the control group was only taking Madopar orally,the dose was as same as the treatment group.To observe cycle of the two groups were both three months.[Results] The treatment group was an effective prescription for tremor type PD,especially at the phychosis,behavior and emotion,ordinary activity,movement function.The difference had a statistical significance between two groups（P0.05）.[Conclusion] Tremor type PD＇s pathogenesis was deficiency of the liver and kidney and Liver-Wind stirs up internally.We took a good healing effect from the treatment of nourish Kidney and Liver to stop endogenous wind.

关 键 词：帕金森病 震颤型 中医药疗法 随机对照试验 

分 类 号：R749[医药卫生—神经病学与精神病学]