驱动蛋白静电作用下的运动机制  

The movement mechanism of kinesin under electrostatic interaction

作　　者：黄艳宾[1] 郑燕[2] 李洁[2] 

机构地区：[1]河北工程大学理学院,河北邯郸056038 [2]邯郸学院物理与电气工程系,河北邯郸056005

出　　处：《河北工程大学学报（自然科学版）》2010年第2期97-100,共4页Journal of Hebei University of Engineering:Natural Science Edition

基　　金：邯郸市科学技术研究与发展计划项目(0021107050);河北工程大学青年基金

摘　　要：本文依据一种驱动蛋白的结晶结构信息建立计算模型,结合生物系统里氨基酸、镁离子和核苷酸的带电性质,通过解泊松方程模拟计算了马达沿微管的静电相互作用,结果显示驱动蛋白在沿微管方向运动时受到了周期性的静电吸引作用,并且其周期与微管结构的周期是相同的;在这个周期性势场的作用下马达顺利的找到了结合位点,完成了静电作用下的运动机制即实现了化学能-机械能-静电能相耦合的周期性定向移动。Kinesin is a kind of molecule motor that moves along the microtubule, and the study of its movement mechanism will help human reveal the energy conversion mechanism of the life systems. In this pa- per, based on the crystal structure of a kinesin motor and simulated by solving Poisson＇ s equation, the electrostatic interactions of kinesin along the microtubule have been calculated, the results show that the electrostatic interactions play an important role when kinesin moves along microtubule, and the interaction periodicity is consistent with the periodicity of microtubule, then we present the mechanism of kinesin under the electrostatic interaction.

关 键 词：驱动蛋白马达 微管 静电相互作用 泊松方程 

分 类 号：Q615[生物学—生物物理学]