可逆性后部脑病综合征:临床和影像学分析  

Clinical and Neuroimaging Characteristics of Reversible Posterior Reversible Encephalopathy Syndrome

作　　者：于凌[1] 于国平[1] 高波[2] 

机构地区：[1]青岛大学医学院附属烟台毓璜顶医院神经内科,山东烟台264000 [2]青岛大学医学院附属烟台毓璜顶医院影像科,山东烟台264000

出　　处：《现代生物医学进展》2010年第11期2095-2096,共2页Progress in Modern Biomedicine

摘　　要：目的:探讨可逆性后部脑病综合征(PRES)的发生机制。方法:回顾性分析45例PRES患者的临床和影像学资料。结果:临床表现为头痛、精神状态改变、癫痫发作和视力改变。病因为高血压、子痫/先兆子痫等。PRES高血压发生率为88.9%,其中超过脑血管自动调节上限的为20.0%。MRI表现为:顶枕叶为主的经典型28例,全脑型9例,不对称型5例,脑干型3例。结论:PRES病理基础为血管源性水肿,影像学表现以经典型为主。Objective：To investigate the pathomechanism of posterior reversible encephalopathy syndrome（PRES）.Methods：The clinical and radiologic data were retrospectively analyzed in forty-five patients.Results：The clinical manifestation included headache, altered mental functioning,epilepsy,visual disturbances.The causes involved hypertension,eclampsia/pre-eclampsia and so on.Forty-five patients with hypertension was 88.9%, over the upper limit of cerebrovascular autoregulation was 20.0%.28 cases with classic parietal-occipital lobe distribution pattern, diffuse type（9 cases）,asy mmetric type（5 cases） and brain stem type（3 cases）.Conclusions：Patho-logical basis of PRES is vasogenic edema, the main is classic parietal-occipital lobe distribution pattern.

关 键 词：脑疾病 血管源性水肿 磁共振成像 

分 类 号：R74[医药卫生—神经病学与精神病学] R816[医药卫生—临床医学]