左旋多巴对屈光参差性弱视患儿视力的影响  

Effects of Levodopa/Cabidopa on visual acuity in childhood amblyopia

作　　者：胡聪[1] 卢秀珍[1] 张辉[1] 李慧[1] 杨先[1] 

机构地区：[1]青岛医学院附属医院,266003

出　　处：《眼视光学杂志》1999年第1期42-43,46,共3页Chinese Journal of Optometry & Ophthalmology

摘　　要：目的：观察息宁（左旋多巴／ 卡比多巴）对难治性屈光参差性弱视患儿视力的影响，探讨左旋多巴用药时间和治疗机理。方法：给３２ 例（５～１５ 岁） 经传统疗法治疗至少６ 个月无效的屈光参差性弱视患儿口服息宁１ｍｇ／０．２５ｍｇ／ｋｇ，一日三次，连续６０ 天。观察服药前及服药后第３、６、９ 、３０、６０ 天单字Ｅ 视力的变化。结果：弱视眼和优势眼的单字视力服药后第３ 天提高，差异有极显著性（ Ｐ＜０ ．０１） ，继续服药无进一步改善。结论：短期服用左旋多巴对改善难治性屈光参差性弱视的视力有一定作用。Objective:To evaluate the effects of Levodops/Carbidopa on visual acuity in children amblyopia.Methods:A 60-day administration of Levodopa/Carbidopa(1/0.25mg/kg,three times daily)was given to 32 children(mean age,9.63 years) with anisometropic amblyopia.Single chart visual acuity was measured at the baseline and 3,6,9,30 and 60 days after administration respectively.Results:Single chart visual acuity were improved significantly in the amblyopic eyes of the children after ingestion of 3 days,than no further improvement.Conclusion:Levodopa/Carbidopa was found to be effcacious in improving visual acuity in amblyopic children in the first drug ingestion.

关 键 词：左旋多巴 卡比多巴 弱视 屈光不正 儿童 

分 类 号：R777.440.5[医药卫生—眼科] R779.705[医药卫生—临床医学]