结肠癌伴同时性肝转移手术治疗及预后分析  

作　　者：温华生[1] 郝俊[1] 

机构地区：[1]广州医学院附属深圳沙井医院普外科,518104

出　　处：《中国社区医师（医学专业）》2010年第19期48-49,共2页

摘　　要：目的:探讨结肠癌肝转移的手术治疗及影响预后的因素分析。方法:收集1999年8月～2008年3月结肠癌同时性肝转移行手术治疗病例42例,探讨影响患者预后的因素。结果:患者1年生存率73.8%,3年生存率47.6%。性别、发病年龄、肿瘤发生部位、原发肿瘤浸润程度、淋巴结转移、术前CEA水平、原发结肠癌周径等因素对结肠癌同时性肝转移行手术治疗的患者预后有显著性影响(P<0.05)。肿瘤分化程度、转移灶数量和大小、手术方式对此类患者3年生存时间有显著性影响(P<0.05)。结论:肿瘤分化程度、转移灶数量及体积,和采用的手术方式对结肠癌伴同时性肝转移患者的预后判断有一定作用。Objective：To investigate the surgical treatment and the prognosis of coloreetal cancer with simultaneous hepatic metastasis.Methods：From Aug.1999 to Mar.2008,42 cases of colorectal carcinoma with synchronous liver metastases receiving surgical therapy were admitted.Results were analyzed retrospectively using the software of SPSS.Results：The survival rates at 1 and 3 years were73.8% and 47.6% respectively.Sex,age,area and perimeter of the tumor,CEA level before surgery,lymphatic metastasis,depth of invasion and pathological type had no effect on predicting the prognosis（P〈0.05）.The differetiation,single and small metastasis,and radical surgery leads to a better prognosis（P〈0.05）.Conclusion：The degree of differetiation,number and volume of metastasis in liver,and operation way were significant factor predicting the prognosis of colorectal cancer with synchronous liver metastases.

关 键 词：结肠癌 肿瘤 转移 

分 类 号：R735.2[医药卫生—肿瘤]