中草药对肺癌化疗的增效解毒作用观察——附235例病例分析  

Observation of the effects of traditional Chinese herbs on chemotherapy sensitivity and toxicity of lung cancer:Analysis of 235 cases

作　　者：肖军[1] 张勇[1] 杨新玲 陈刚[1] 梁欣[1] 

机构地区：[1]山东省肿瘤防治研究院内四科

出　　处：《齐鲁肿瘤杂志》1999年第1期35-37,共3页

摘　　要：目的观察中草药对肺癌化疗疗效及化疗毒性反应的影响。方法以１９９４年～１９９７年在我院住院治疗的１３９例肺癌患者作为治疗组，采用以ＤＤＰ为主的联合化疗，同时配合服用中药汤剂。并以同期住院的９６例患者作为对照组，单纯采用以ＤＤＰ为主的联合化疗。结果治疗组近期有效率显著高于对照组（Ｐ＜０．０５）。在消化道毒性、骨髓抑制毒性、肝脏毒性方面，治疗组毒性反应显著低于对照组（Ｐ＜０．０１）。结论中草药可有效的防治肺癌化疗过程中出现的毒性反应，且对化疗有显著的增敏增效作用。Objective To observe the effects of traditional Chinese herbs on chemotherapy sensitivity and toxicity of chemotherapy.Method A study control trial in 235 patients with lung cancer in our hospital from 1994 to 1997 were performed.139 patients of study group were treated with Chinese herb medicine plus combined chemotherapy,96 patients of control group were treated with combined chemotherapy alone.Results The difference of effective rates between trial group and control group was obvious (P<0.05),and the toxicities of chemotherapy on digestive duct,bone marrow and liver in trial group were less than those in control group (P<0.01).Conclusion Chinese herb medicine can not only prevent the side effects of chemotherapy of lung cancer but also enhance the effect of chemotherapy.

关 键 词：肺癌 增效解毒 药物疗法 中西医结合治疗 

分 类 号：R734.205[医药卫生—肿瘤] R730.59[医药卫生—临床医学]