血脂康对脑梗死患者颈动脉粥样硬化斑块及C反应蛋白的影响  

Impacts of Xuezhikang on the carotid artery atherosclerotic plaque and CRP in patients with cerebral infarction

作　　者：唐永亮[1,2] 张子诚[1,2] 苏东升[1,2] 张雷[1,2] 宇辉[1,2] 张诚[1,2] 薛庆华[1,2] 仝德章[1,2] 钟平[1,2] 

机构地区：[1]安徽医科大学宿州临床学院 [2]宿州市立医院干部病房神经内科,宿州234000

出　　处：《中国实用神经疾病杂志》2010年第13期13-15,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨长期服用血脂康对脑梗死患者的颈动脉粥样硬化斑块和血清C反应蛋白(CRP)的影响。方法 61例有动脉粥样斑块的脑梗死患者随机分为血脂康组和对照组,利用彩色多普勒超声仪测量患者颈动脉中-内膜厚度(IMT)和粥样斑块大小,并检测血清CRP水平和总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)及高密度脂蛋白(HDL-C)水平。观察治疗24周后上述指标的变化。结果治疗后血脂康组CRP水平、TC、TG、LDL-C明显下降,HDL-C明显升高;IMT和粥样斑块变小,且差异具有统计学意义。结论血脂康具有抗炎,抗动脉粥样硬化,逆转粥样硬化斑块的作用,进而对脑梗死的发生起预防作用。Objective To investigate the impacts of long-term use of Xuezhikang in patients with cerebral infarction to the carotid artery atherosclerotic plaque and C-reactive protein （CRP）. Methods Sixty-one cerebral infarction patients with carotid atherosclerosis were randomly divided into Xuezhikang group and control group. Color Doppler ultrasound wad used to measure carotid artery-intima-media thickness （IMT） and plaque size, and to detect the level of C-reactive protein levels and total cholesterol （TC）, triglyceride（TG）, low density lipoprotein （LDL-C） and high density lipoprotein （HDL-C） in serum for patients administrated Xuezhikang; The changes of the above-mentioned indicators were observed before and after application of Xuezhikang. Results After 24 weeks of application of Xuezhikang, C-reactive protein levels, TC, TG, and LDL-C decreased, HDL- C significantly increased, IMT and plaque become smaller, and the difference was statistically significant. Conclusion Xuezhikang plays a role in anti-inflammatory, anti-atherosclerosis, atherosclerotic plaque reversal, and thus may prevent occurrence of cerebral infarction.

关 键 词：血脂康 动脉粥样硬化 脑梗死 C反应蛋白 

分 类 号：R743.33[医药卫生—神经病学与精神病学]