依达拉奉联合高压氧治疗一氧化碳中毒迟发性脑病的临床研究  

Effect of edaravone combined hyperbaric oxygen therapy in delayed encephalopathy after acute carbon monoxide poisoning

作　　者：李立新[1] 王海合[1] 郭志勇[1] 贾平方 崔燕[3] 

机构地区：[1]河南新乡市第一人民医院神经内科,新乡453000 [2]河南新乡市第二人民医院神经内科,新乡453000 [3]河南新乡市第一人民医院高压氧治疗室,新乡453000

出　　处：《中国实用神经疾病杂志》2010年第13期20-22,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨依达拉奉联合高压氧治疗一氧化碳中毒迟发性脑病的临床疗效。方法将70例一氧化碳中毒后迟发性脑病患者随机分为治疗组和对照组各35例,对照组给予高压氧及综合治疗,对照组在此基础上加用达拉奉,在治疗前和治疗后30 d进行临床疗效评定。结果治疗组总有效率88%,明显优于对照组。结论依达拉奉联合高压氧治疗一氧化碳中毒发性脑病(DEACMP)疗效确切。Objective To investigate the clinical effect of edaravone combined hyperbaric oxygen therapy in delayed encephalopathy after acute carbon monoxide poisoning （DEACMP）. Methods Seventy cases of DEACMP were randomly divided into treatment group and control group, 35 cases in treatment group were treated by the hyperbaric oxygen therapy with the edaravone based on the internal comprehensive treatment, 35 cases in control group were treated only by the hyperbaric oxygen therapy based on the internal comprehensive treatment. The clinical effect was evaluated in the treatment of 30 days before and after treatment. Results The total effective rate was 88% in treatment group, the clinical effect in treatment group was significantly superior to those in the control group. Conclusion The study suggests that edaravone combined hyperbaric oxygen therapy is an effective therapy in the patients with DEACMP.

关 键 词：一氧化碳中毒 迟发性脑病 高压氧 依达拉奉 

分 类 号：R742[医药卫生—神经病学与精神病学]