可逆性后部白质脑病综合征13例临床和影像学分析  

THE CLINICAL AND IMAGING ANALYSIS OF 13 CASES OF REVERSIBLE POSTERIOR LEUKOENCEPHALOPATHY SYNDROME

作　　者：周亮[1] 刘学政[1] 肖延华[1] 

机构地区：[1]井冈山大学医学院,江西吉安343000

出　　处：《井冈山大学学报（自然科学版）》2010年第4期97-100,共4页Journal of Jinggangshan University (Natural Science)

摘　　要：目的探讨可逆性后部白质脑病综合征(RPLS)的临床和影像学特点,提高对RPLS的认识。方法对13例RPLS的临床资料进行回顾性分析总结并复习文献资料。结果 RPLS的主要临床表现为:头痛、意识障碍、癫痫发作、视觉障碍、精神异常、共济失调、偏瘫等。神经影像学以双侧对称性大脑后部白质为主的异常信号,也可累及皮层。经及时有效治疗后,症状、体征以及影像学改变可完全恢复。结论 RPLS的诊断主要以特征性的临床表现和神经影像学特点为依据,早期诊断、及时治疗是可逆性转归的关键。Objective：To investigate the clinical manifestation and imaging features of reversible posterior leukoencephalopathy syndrome（RPLS）.Methods：The clinical data of 13 cases of RPLS were analyzed retrospective1y,and the literature of RPLS were reviewed.Result：The clinical manifestation of RPLS included headache,consciousness disorders,seizure disorder,vision disorders, emotionai disturbance,ataxy, hemiparalysis and so on.The abnormal signals of neuroradiologic imaging predominantly showed symmetrical lesions in the posterior cerebral white matter bilaterally,and also involved the cortex.The clinical symptom,signs and neuroradiologic imaging changes could completely recovered after prompt and effective treatment.Conclusions：The diagnosis of RPLS main1y depended on the clinical symptom and neuroradiologic features.Early diagnosis and therapy were very critical for the prognosis.

关 键 词：可逆性后部白质脑病综合征 临床 磁共振成像 

分 类 号：R742[医药卫生—神经病学与精神病学]