CT、MRI和PET-CT对鼻咽癌颈部淋巴结转移检测差异的初步研究  

Preliminary studies of differences in detecting cervical lymph node metastasis of nasopharyngeal carcinoma using CT,MRI and PET-CT

作　　者：杨红茹[1] 向莉[1] 秦朝军[2] 黄盛才[2] 王仁生[3] 

机构地区：[1]泸州医学院附属医院肿瘤科,四川泸州646000 [2]广西医科大学第一附属医院PET-CT中心,南宁530021 [3]广西医科大学第一附属医院放疗科,南宁530021

出　　处：《重庆医学》2010年第14期1794-1797,共4页Chongqing medicine

基　　金：广西医疗卫生重点科研课题基金资助(重200527)

摘　　要：目的比较CT、MRI和18FDG-PET-CT对鼻咽癌颈部淋巴结转移的检测差异,并探讨PET-CT对鼻咽癌颈部淋巴结转移检测的应用价值。方法 68例鼻咽癌患者,放疗前1周内完成增强CT、增强MRI和PET-CT扫描检查。结果应用CT、MRI和PET-CT分别检出咽后淋巴结转移18例(26.47%)、42例(61.76%)和20例(29.41%),3种检查差异有统计学意义(χ2=10.940,P=0.004),MRI与CT、MRI与PET-CT比较差异有统计学意义(分别χ2=8.589,P=0.003和χ2=7.173,P=0.007),CT与PET-CT比较差异无统计学意义。应用CT、MRI和PET-CT分别检出颈部淋巴结转移42例(61.76%)124个、42例(61.76%)128个和38例(55.88%)120个,3种检查方法结果比较差异无统计学意义(χ2=0.326,P=0.849),PET-CT对部分最短直径小于10 mm的淋巴结可确诊。结论对鼻咽癌咽后淋巴结转移的检测,MRI较CT和PET-CT有明显优势;对鼻咽癌颈部淋巴结转移的检测,PET-CT较CT和MRI无明显优势;PET对部分最短直径小于1 cm的淋巴结可确诊。Objective To compare the differences in diagnosis of cervical lymph node metastasis of nasopharyngeal carcinoma among CT,MRI and PET-CT and to explore the value of using 18FDG-PET-CT detection for nasopharyngeal carcinoma（NPC）.Methods 68 cases of squamous cell carcinoma of NPC were enrolled in the study.Before treatment,CT,MRI and 18FDG-PET-CT scanning were performed.Results Among 68 cases,positive detection rates of retropharyngeal lymph node metastasis were 26.47%（18/68）,61.76%（42/68）and 29.41%（20/68）.There had statistical significance among CT,MRI and PET-CT（χ2 =10.940,P=0.004）,between MRI and CT（χ2 =8.589,P=0.003） and between MRI and PET-CT（χ2 =7.173,P=0.007）.Positive detection rates of cervical lymph node metastasis were 61.76%（42/68）,61.76%（42/68）and 55.88%（38/68）based on CT,MRI and PET-CT respectively.There had no statistical significance among CT,MRI and PET-CT（χ2=0.326,P=0.849）.PET-CT was superior than MRI and CT in detecting the cervical lymph node metastasis which minimum diameter 1 cm.Conclusion MRI has obvious advantage in detecting retropharyngeal lymph node metastasis of nasopharyngeal carcinoma compared to CT and PET-CT.PET-CT has no advantage in detecting cervical lymph node metastasis of nasopharyngeal carcinoma compared to CT and MRI.PET-CT has a remarkable advantage in detecting cervical lymph node metastasis which minimum diameter 1 cm.

关 键 词：鼻咽肿瘤 磁共振成像 X线计算机体层摄影 18FDG-PET-CT 

分 类 号：R739.63[医药卫生—肿瘤]