原发性大肠恶性淋巴瘤临床表现、内镜与病理特点  

Clinical manifestation,endoscopic and pathologic character of primary colorectal malignant lymphoma

作　　者：温静[1] 梁浩[1] 郭明洲[1] 

机构地区：[1]解放军总医院消化内科,北京100853

出　　处：《胃肠病学和肝病学杂志》2010年第7期634-635,共2页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨原发性大肠恶性淋巴瘤(PCML)的临床表现、内镜和病理特点。方法回顾性分析经病理证实的34例PCML的临床和内镜资料。结果34例患者主要症状为腹痛、体重下降、发热、腹块、血便和大便习惯改变。肿瘤位于回盲部11例,回肠末段10例,横结肠1例,乙状结肠1例,直肠3例,多部位者8例。内镜下为息肉型5例(14.7%),溃疡型17例(50.0%),浸润型12例(35.3%)。病理类型均为非何杰金淋巴瘤。肿瘤起源于B淋巴细胞31例,T淋巴细胞3例。结论原发性大肠恶性淋巴瘤临床表现多不典型。回盲部发病率最高,内镜及大体分型以溃疡型多见。组织病理学检查是确诊本病的主要手段。Objective To explore the clinical manifestations,endoscopic and pathologic characteristics of primary colorectal malignant lymphoma. Methods The clinical,pathologic and endoscopic data of 34 cases of primary colorectal malignant lymphoma in our hospital were analyzed retrospectively. Results Among 34 cases,the most common symptoms were abdominal pain,loss of weight,fever,abdominal mass,blood in stools,and the change in bowel habits.Eleven cases located in ileocecal region,10 in terminal ileum,1 in transverse colon,1 in sigmoid colon,and 3 in rectum.These patients were all examined by endoscopy with polypoid（n=5,14.7%）,ulcerative（n=17,50.0%） and infiltrative（n=12,35.3%）.Pathological types were all non-Hodgkin＇s lymphoma.The tumor originated from the following organisms： B cell（n=31）,T cell（n=3）. Conclusion The primary colorectal malignant lymphoma affecting frequently the ileocecal region as ulcerative growth has no specific clinical manifestation.Histopathology is the main diagnosis method.

关 键 词：恶性淋巴瘤 非何杰金氏病 大肠 

分 类 号：R735.34[医药卫生—肿瘤]