脉冲电磁场和功能矫形对大鼠下颌髁突IGF-I表达影响的研究  

Studies on the effects of pulsating electromagnetic fields and functional appliances on the changes of rat mandibular condylar insulin like growth factor I expression

作　　者：周征[1] 李小兵[1] 郭宏铭[1] 赵美英[1] 罗颂椒[1] 

机构地区：[1]华西医科大学口腔医学院

出　　处：《临床口腔医学杂志》1999年第1期10-11,共2页Journal of Clinical Stomatology

基　　金：国家自然科学基金;卫生部科研基金

摘　　要：将２０只青春期雄性ＳＤ大鼠随机等量分为对照组，脉冲电磁场（ＰＥＭＦ）组，戴功能矫治器（ＦＡ）组及二者共同作用（ＰＥＭＦ＋ＦＡ）组，研究脉冲电磁场和功能矫治器对大鼠下颌髁突胰岛素样生长因子Ｉ（ＩＧＦ—Ｉ）表达变化。经过１０天的实验，结果发现ＰＥＭＦ和功能矫治器都可显著性增加髁突软骨细胞的ＩＧＦ—Ｉ表达，提示二者具有协同作用，为临床联合使用ＰＥＭＦ和ＦＡ进行下颌骨的矫形治疗提供了实验依据。Twenty male 5 week old growing SD rats were equally and randomly divided into four groups: control group, pulsating electromagnetic field (PEMF) group, functional appliances (FA) group, combining PEMF and FA group. After 10 days experiment, the result showed: both PEMFand FA could significantly increase insulin like growth factor I(IGF I) expression in rat mandibular condylar cartilage cells( P <0.05). It suggested that PEMF can enhance the orthopedic effect of functional appliances.

关 键 词：脉冲电磁场 功能矫形 下颌骨 IGF-Ⅰ 

分 类 号：R782.23[医药卫生—口腔医学]