山东招远阜山镇两个自然村高尿酸血症与痛风患病状况调查  

SURVEY OF HYPERURICEMIA AND GOUT IN TWO VILLAGES OF FUSHAN TOWNSHIP OF ZHAOYUAN IN SHANDONG PROVINCE

作　　者：王琨[1] 付正菊[1] 李长贵[1] 刘世国[1] 苗志敏[1] 阎胜利[1] 王颜刚[1] 孟冬梅[1] 韩琳[1] 

机构地区：[1]青岛大学医学院附属医院内分泌科,山东青岛266003

出　　处：《青岛大学医学院学报》2010年第5期380-383,共4页Acta Academiae Medicinae Qingdao Universitatis

基　　金：国家自然科学基金资助项目(30470821)

摘　　要：目的明确招远阜山镇九曲村与黄金村居民高尿酸血症与痛风的患病状况,并对其危险因素进行初步分析。方法对招远阜山镇九曲村与黄金村2个自然村居民高尿酸血症与痛风的患病状况进行调查。结果两村高尿酸血症、痛风的患病率比较差异有显著性(χ2=7.352、8.399,P<0.05)。非条件Logistics回归分析显示,肥胖及吸烟是女性高尿酸血症与痛风的独立危险因素;腹型肥胖及饮酒是男性高尿酸血症与痛风的独立危险因素。而高三酰甘油血症、舒张压升高及海鲜摄入量的增加是男女共有高尿酸血症与痛风的独立危险因素。结论九曲村居民高尿酸血症和痛风的患病率明显高于黄金村考虑与海产品的摄入频率与摄入量有关。减少海鲜的摄入量及频率、戒烟、戒酒、控制体质量、纠正糖脂代谢紊乱、控制高血压、增加体力活动和体育运动等是降低血尿酸和减少痛风发作的重要措施。Objective To make clear the prevalence of hyperuricemia and gout in Fushan area and analyze the risk factors.Methods An investigation of hyperuricemia and gout was carried out in residents of two villages,Jiuqu and Huangjin,of Fushan township.Results The prevalence of hyperuricemia and gout was 16.46% and 2.29% in Jiuqu village,and 9.64% and 0.27% in Huangjin village,the difference being significant（χ^2=7.352,8.399;P〈0.05）.Non-conditional logistic regression ana-lysis showed that obesity and smoking were independent risk factors for females;for males,the risk factors were abdominal obesity and alcohol.Hypertriglyceridemia,elevated DBP and increase of sea food intake were independent risk factors for males and females.Conclusion The prevalence of hypertriglyceridemia and gout are significantly higher in Jiuqu than in Huangjin village,which is considered to be associated with the frequency and quantity of seafood intake.Reducing seafood intake,stop smoking and drinking,control of body weight,correction of glucolipid metabolic disorder,hypertension control,increase physical activity and athletic sports are important measures to decline blood uric acid and decrease the onset of gout.

关 键 词：高尿酸血症 痛风 患病率 因素分析 统计学 招远 

分 类 号：R589.7[医药卫生—内分泌]