颅内动脉狭窄对进展性卒中的影响  

THE EFFECT OF INTRACRANIAL ARTERIAL STENOSIS ON PROGRESSIVE STROKE

作　　者：王鹏飞[1] 赵仁亮[1] 王国峰[1] 赵俊武[1] 

机构地区：[1]青岛大学医学院附属医院神经内科,山东青岛266003

出　　处：《青岛大学医学院学报》2010年第5期457-459,462,共4页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：目的探讨颅内动脉狭窄、闭塞及侧支循环的程度与进展性卒中的关系。方法收集发病24h内入院的急性脑梗死病人285例,记录病人入院时的基线资料、实验室检查资料,在入院时及入院72h后两次评价病人的神经功能。将入院72h后NIHSS评分增加≥2分者定义为进展性卒中。应用西门子3.0T磁共振血管成像(MRA)评价颅内血管狭窄、闭塞及侧支循环。结果 285例病人中有57例(20.0%)为进展性卒中。多因素Lo-gistic回归分析显示,颈内动脉狭窄或闭塞、大脑中动脉狭窄或闭塞、基底动脉狭窄或闭塞、3级侧支循环、糖尿病史是进展性卒中的独立危险预测指标。结论进展性卒中是比较常见的卒中类型,通过MRA显示的血管狭窄、闭塞及侧支循环的程度能有效地预测进展性卒中的发生。Objective To investigate the relationship between intracranial arterial stenosis（ICAS）,arterial occlusion（AO）,the extent of collateral circulation（CC）and progressive stroke（PS）.Methods Data of 285 patients admitted to hospital within 24 hours of the onset of acute cerebral infarction（ACI）were collected.Baseline information,laboratory findings and neurofunction were recorded.Based on the score of National Institutes of Health Stroke Scale（NIHSS）for patients hospitalized after 72 hours plus ≥2 marks were defined as PS.3.0 T magnetic resonance angiography was used for assessment of ICAS,AO and CC.Results Of the 285 patients,57（20.0%）were diagnosed as PS.Multivariate logistic regression analysis showed that stenosis/occlusion in internal carotid artery,in middle cerebral artery,in basilar artery,3rd-degree CC and a history of diabetes mellitus were independent risk predictors of PS.Conclusion PS is a relatively common type of stroke,intracranial arterial stenosis/occlusion and the extent of collateral circulation showed in magnetic resonance angiography imaging may predict the occurrence of this condition.

关 键 词：脑血管意外 颈动脉狭窄 大脑中动脉 基底动脉 侧支循环 

分 类 号：R743.3[医药卫生—神经病学与精神病学]