胶质瘤磁敏感成像表现及与病理对照  

Manifestations of susceptibility weighted imaging of glioma with pathologic correlation

作　　者：吴先衡[1] 林时勖[1] 陈少贤[1] 林斯宏[1] 曾向廷[1] 林黛英[1] 沈金辉[2] 许海雄[3] 刘明发[3] 

机构地区：[1]汕头市中心医院放射科,广东515031 [2]汕头市中心医院病理科,广东515031 [3]汕头市中心医院神经外科,广东515031

出　　处：《放射学实践》2010年第7期723-725,共3页Radiologic Practice

基　　金：广东省医学科研基金立项项目(A2009646)

摘　　要：目的:探讨磁敏感加权成像(SWI)在胶质瘤分级诊断中的作用。方法:25例经手术病理证实的脑胶质瘤患者术前均行MRI平扫、增强和SWI检查,11例患者行MRS检查。由两位高年资神经放射诊断医师对SWI肿瘤内的低信号进行评分,并与病理学结果对照分析。结果:14例高级别胶质瘤中12例瘤内出现不同程度多发斑片状、索状低信号,病理学证实为瘤内出血及瘤内血管;11例低级别胶质瘤中3例瘤内未出现明显低信号,6例瘤内出现少许斑点、线状低信号,病理证实为瘤内血管,2例瘤内可见少量斑片状低信号,病理证实为瘤内出血。高级别组胶质瘤内低信号评分值高于低级别组(P<0.05)。结论:不同级别胶质瘤在磁敏感加权成像表现有明显差异,SWI有助于术前对胶质瘤分级进行评估。Objective：To explore the role of susceptibility weighted imaging（SWI）in the grading of gliomas.Methods：25 cases of glioma confirmed by surgical pathology were collected.MRI plain,enhanced and SWI scans were performed.Magnetic resonance spectroscopy（MRS）in 11 of them was also performed for analysis.Two senior neuro-radiologists surveyed and graded the low-intense signals in the tumors on SWI and pathologic correlation was studied.Results：Varying drgrees of intratumoral multiple patchy or rope-like low-intense signals were present in 12 of 14 cases of high-grade gliomas and intratumoral hemorrhge and vasculature was observed on pathology.In 11 cases of low-grade glioma no obvious low-intense signal was noted in 3,and a few patchy stippled,linear low-intense signals were noted in 6,which were confirmed by pathology to be intratumoral blood vessels;a small amount of patchy low-intense signals were observed in the rest 2 cases and this was confirmed pathologically to be intratumoral hemorrhage.Low-intense signal score in high-grade gliomas is higher than that in low-grade gliomas（P〈0.05）.Conclusion：Different grades of glioma show obvious different signification on susceptibility weighted imaging（SWI）,probably be helpful for evaluation of glioma grading preoperatively.

关 键 词：脑肿瘤 磁共振成像 磁敏感加权成像 病理学 

分 类 号：R739.4[医药卫生—肿瘤]