PET/CT在儿童及青少年肿瘤患者中的应用  

Application of PET/CT in children and young adults with tumor

作　　者：罗亚平[1] 朱朝晖[1] 李方[1] 霍力[1] 崔瑞雪[1] 牛娜[1] 张迎强[1] 李从心[1] 赵海燕[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院核医学科,北京100730

出　　处：《癌症进展》2010年第4期328-334,共7页Oncology Progress

摘　　要：目的评价PET/CT在年轻肿瘤患者中的应用价值。方法回顾性分析我院行躯干PET/CT检查且年龄≤25岁的病例,共75例(男性35例,女性40例)89次检查。结果所患肿瘤前三位依次为淋巴瘤(31%)、卵巢肿瘤(16%)和神经内分泌肿瘤(8%)。PET/CT用于协助诊断(42%)、分期(11%)、疗效评估(27%)和复发监测(30%)。PET/CT对63%(22/35)的淋巴瘤诊断、分期、治疗评估和复发监测有重要意义,改变了58%(7/12)的卵巢肿瘤患者的诊疗决策,对40%的其他肿瘤患者有帮助。对年轻患者的图像分析须注意胸腺、卵巢和子宫内膜等生理性摄取。结论 PET/CT对于指导儿童和青少年肿瘤诊疗具有较大价值,可在权衡辐照危害后合理选用。Objective To evaluate the application of PET/CT in children and young adults with tumor. Methods The clinical data of 75 children and young aduhs （ ≤25y, 35 males, 40 females） who underwent a total of 89 PET/CT scans for evaluation of tumors in Peking Union Medical College Hospital were retrospectively analyzed. Results In this group of patients, the most common malignancies were lymphoma （31%） , genital （ovarian） tumor （16%） , and neuroendoerine tumor （8%）. The purposes of PET/CT examination included diagnosis （42%）, staging （11%）, evaluation after therapy （ 27% ） , and surveillance of residual or recurrent lesions （ 30% ）. PET/CT provided important imformation for 63 % （22/35） of lymphama in terms of diagnosis, staging, effectiveness evaluation, and recurrence monitoring. It changed the treatment decision-making in 58% （7/12） of patients with genital tumors. It was also helpful for 40% of patients with other tumors. Conclusion PET/CT is valuable for children and young adults with tumors and should be properly used after balancing the radiation risks.

关 键 词：正电子发射断层显像 计算机断层摄影术 肿瘤 儿童 青少年 

分 类 号：R817.44[医药卫生—影像医学与核医学] R730.44[医药卫生—放射医学]