AgNOR对急性白血病分型诊断意义的再评价  

Appraise significance of AgNOR staining in the diagnosis of acute leukemia classification

作　　者：许朝晖[1] 于增国[2] 王永才[3] 

机构地区：[1]大连医科大学附属第一医院检验科,大连116011 [2]辽宁省大连大学医学院,116022 [3]大连医科大学附属第二医院检验科,大连116027

出　　处：《中国医疗前沿》2010年第12期70-70,76,共2页China Healthcare Innovation

摘　　要：目的研究AgNOR染色在急性白血病分型诊断中的意义。方法用银染技术观察212例急性白血病骨髓片,122例血片,43例正常对照组的细胞AgNOR数/核,与正常比较找出相关性。结果急性白血病呈显著增高,平均AgNOR4.43±0.98/核,而正常人AgNOR1.49±0.37/核,两者比较,经统计学处理白血病组显著高于正常对照组,差异有显著性意义(p<0.01)。结论 AgNOR有助于急性白血病诊断及鉴别诊断,可作为急性白血病早期前瞻性诊断指标。Objective Significance of AgNOR staining in the diagnosis of acute leukemia classification.Methods Observe with silver staining technology 212 cases of acute leukemia bone marrow films,122 cases of blood film,and 43 normal controls of cell AgNOR number/nucleus,compare with the normal cases and find the relevance.Results the average AgNOR 4.43±0.98/nuclear is significantly higher in acute leukemia,while in normal persons only AgNOR 1.49± 0.37/nuclear,the difference is of great significance （p〈 0.01）.Conclusion AgNOR can help diagnose and differentiate diagnosis of acute leukemia,and can be used in early diagnosis of acute leukemia.

关 键 词：AGNOR 急性白血病 早期诊断 

分 类 号：R446.6[医药卫生—诊断学] R733.7[医药卫生—临床医学]