不同照射方式治疗70例双侧咽旁间隙受侵鼻咽癌的疗效观察  

The Radiotherapy Effects of 70 Cases of Nasopharyngeal Carcinoma with Involvement of Bilateral Pharyngeal Space Treated by Different Protocols

作　　者：黄河澄[1] 文之斐[1] 刘庆深[1] 陈纯真[1] 林连兴[1] 

机构地区：[1]汕头市中心医院放疗科,515031

出　　处：《中国实用医药》2010年第21期8-9,共2页China Practical Medicine

摘　　要：目的观察比较70例双侧咽旁间隙侵犯的鼻咽癌患者采用两种不同照射方式治疗的疗效。方法 70例双侧咽旁间隙侵犯的鼻咽癌全部病例经病理和CT证实,随机分成两组:对照组和放疗组各35例。对照组采用面颈联合野放疗至36Gy,鼻咽改用双耳前野、耳后电子束野,颈部采用颈前分割野放疗。放疗组采用面颈联合野放疗至36Gy,自己设计的颈后分割野,并将颈后分割野提高扩大至外耳孔上缘,同时使用双外侧挡块保护双下颌支。结果治疗组咽旁肿物消退率明显高于对照组。结论对于双侧咽旁间隙受侵的鼻咽癌患者,我们设计改进的颈后分割野能明显提高疗效。Objective To compare the radiotherapy effects of 70 cases of nasopharyngeal carcinoma with involvement of bilateral pharyngeal space treated by different protocols. Methods 70 cases of nasopharyngeal carcinoma with bilateral pharyngeal space invasion were confirmed by pathology and CT scan. The patients were. divided into two groups randomly. （ treatment group and control group ）. Each one has 30 patients. The control group adopted lateral faciocervial portal with total dose 36Cy firstly. Then adopted pre-andpost-auricular fields,. The treatment group adopted lateral faciocervial latleral portal firsdy. Then the neck adopted retrocervial partition portal. Which designed by ourselves,We enlarge the portal to the exterior auditory meatus. Results The local control rate in treatment group were higher than in the control group. Radiospinitis and radioactive brain injury in treatment group was no different from that of control group ,（ P〉0. 05 ）. Conclusion The ret-rocervial partition portal. Which designed by ourselves,can be considered as an effective and feasible approach to treat nasopharyngeal carcinoma with involvement of bilateral pharyngeal space.

关 键 词：鼻咽肿瘤/放射治疗 咽旁间隙侵犯 

分 类 号：R739.63[医药卫生—肿瘤]