GATA3与乳腺癌发生发展关系的研究进展  

Relationship of GATA3 with development and progression of breast cancer

作　　者：谢轶群[1,2] 施俊义[1] 李曦洲[1] 隋金珂[1] 

机构地区：[1]第二军医大学长海医院普通外科,上海200433 [2]上海市黄浦区中心医院乳腺外科,上海200002

出　　处：《第二军医大学学报》2010年第7期787-789,共3页Academic Journal of Second Military Medical University

摘　　要：GATA3转录因子在正常乳腺的生长分化中起重要作用,与乳腺癌的发生发展也密切相关,GATA3在不同乳腺癌亚型发生中的作用有所不同。本文综述了GATA3与正常乳腺及乳腺癌发生发展关系的研究现状,为今后研究GATA3在乳腺癌中的临床应用提供理论依据。GATA3 transcription factor plays an important role in the growth and differentiation of normal breast tissues,and it is also closely related to the tumorigenesis of breast cancer.The roles of GATA3 vary in different breast cancer subtypes.This paper reviews the relationship of GATA3 with normal breast tissue and the tumorigenesis of breast cancer,in an attempt to provide theoretical evidences for future clinical applications of GATA3 in breast cancer.

关 键 词：GATA3转录因子 乳腺肿瘤 乳腺 

分 类 号：R737.9[医药卫生—肿瘤]