色素内镜下氩离子凝固术治疗单个隆起型胃黏膜上皮内瘤变16例  

Staining gastroscopic argon plasma coagulation for treating single protruded gastric intraepithelial neoplasia in 16 cases

作　　者：李小刚 吴云林[2] 陈锡美[3] 王志荣[3] Li Xiaogang, Wu Yunlin, Chert Ximei,et al. （Dachang hospital,Shanghai 200436 China）

机构地区：[1]上海市大场医院,上海200436 [2]上海交通大学医学院附属瑞金医院 [3]上海同济大学附属同济医院

出　　处：《中国保健》2009年第16期681-682,共2页

摘　　要：目的：评价色素内镜下氩离子凝固术（APC）治疗单个隆起型胃的癌前病变——上皮内瘤变的价值及安全法。方法：选择三家医院共16例门诊或住院的单个隆起型胃黏膜上皮内瘤变（IEN）的患者先行普通内镜、色素内镜检查和病理组织学检查，之后予以内镜下氩离子凝固术治疗。所有病例治疗6个月后进行临床随访、内镜及病理组织学复查。结果：15例（93．75％）患者临床症状减轻，复查胃镜示原病灶消失，复查病理组织学检查示胃黏膜上皮内瘤变消失，尚存慢性浅表性、萎缩性或浅表一萎缩性炎症，1例（6．25％）仍为局灶性低级别上皮内瘤变（LGIEN），再次行APC治疗。结论：APC为经内镜非接触性治疗单个隆起型胃的癌前病变的新的有效方法，治疗胃的癌前病变方便、快捷、安全。Objective：To evaluate the clinical value and safety of argon plasma coagulation（APC） in the staining gastroscopic treatment of single proturded gastric precancerous lesion - intraepithelial neoplasia. Methods： 16 outpatient oder inpatient cases with intraepithelial neoplasia （IEN） were examined under endoseopy,staining endoscopy and histopathology. They were treated by using APC under endoscopy. All cases were recheehed by endoscopy and histopathology after 6 months. Results：Fifteen patients （93, 75 % ） were alleviated in clinical symptoms. The endoscopic and histopathologic recheck shewed that the intraepithelial neoplasia healed and had been covered by chronic superficial gattritis, chronic atrophic gastritis or chronic superficial - atrophic gastritis. Low grade intraepithelial neoplasia（LGIEN） was locally remained by histopathology in 1 patient （6. 25% ） who was treated again by APC. Conchlsion：APC is an alternative,non -touched technique via endoscopy and new method in the treatment of single protruded stomachal precancerous lesion. It can make the treatment simple, safe and effective.

关 键 词：氩离子凝固术 色素胃镜 癌前病变 胃 

分 类 号：R730.56[医药卫生—肿瘤;医药卫生—临床医学]