西黄丸联合化疗治疗晚期食管癌18例临床观察  

Clinical observation on Xihuang Pill combined with chemotherapy in treating 18 cases of advanced esophageal cancer

作　　者：程志强[1] 朱文婷[2] 

机构地区：[1]中日友好医院中西医结合肿瘤科,北京100029 [2]北京中医药大学,北京100029

出　　处：《中华中医药杂志》2010年第8期1302-1304,共3页China Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:观察西黄丸联合化疗治疗晚期食管癌的临床疗效。方法:晚期食管癌患者35例,随机分为治疗组18例和对照组17例,对照组,奈达铂(NDP)40mg/m2,第1-2d;5-Fu400mg/m2,第1-5d;CF200mg/m2,第1-5d。治疗组于化疗同日开始用西黄丸,化疗方案同对照组。观察两组患者在生活质量、血液学毒性、近期疗效及症状方面治疗前后的差异。结果:治疗组在生活质量提高程度、部分症状缓解率明显优于对照组,血液学毒性及近期疗效组间比较差异无显著性。结论:西黄丸可提高晚期食管癌的生活质量,缓解部分症状。Objective： To observe the clinical effects on advanced esophageal cancer by combined Xihuang Pill with chemotherapy. Methods： Dividing 35 advanced esophageal cancer cases randomly into two groups： 18 cases in the treatment group and 17 cases in the control group. Cases in the control group were treated by nedaplatin 40mg/m^2,d1,2; 5-Fu400mg/m^2,d1-5; CF200 mg/m^2,d1-5. While the treatment with Xihuang Pill combined. The difference of quality of life, hematological toxicity, efficacy and symptoms between the two groups was observed. Results： The quality of life, remission rate of some symptom in the treatment group were much better than the control group, and the hematological toxicity and efficacy were the same. Conclusion： Xihuang Pill could improve the quality of life of advanced esophageal cancer patient, and alleviate some symptoms.

关 键 词：西黄丸 晚期食管癌 中西医结合 生活质量 症状 临床观察 

分 类 号：R735.1[医药卫生—肿瘤]