脑瘫高危因素与出生胎龄的关系  

Correlation between Risk Factors of Cerebral Palsy and Gestational Age of Live Born Infants

作　　者：王珂 侯梅 孙殿荣 于荣 赵建慧 姜艳平 

机构地区：[1]青岛市妇女儿童保健中心,山东青岛市266011

出　　处：《中国康复理论与实践》2010年第7期617-618,共2页Chinese Journal of Rehabilitation Theory and Practice

摘　　要：目的探讨脑瘫高危因素与出生胎龄的关系及其可能的发病机理。方法回顾性分析478例脑瘫患儿的出生胎龄、高危因素与临床特征。结果宫内窘迫、先兆流产史、母孕期非感染性疾病、缺氧缺血性脑病、新生儿惊厥、新生儿感染、颅内出血及新生儿溶血与患儿出生胎龄无明显相关(P>0.05);脑发育畸形、母孕期感染性疾病、吸入性肺炎、新生儿窒息、高胆红素血症与患儿出生胎龄负相关(P<0.05)。早产儿及足月儿痉挛型双瘫比率有显著性差异(P<0.05)。结论出生胎龄越小,合并脑发育畸形、母孕期感染性疾病、吸入性肺炎、新生儿窒息、高胆红素血症时,其脑性瘫痪患病率越高;早产儿患痉挛型双瘫比例大于足月儿。Objective To determine the correlation between the risk factors of cerebral palsy and gestational age of live born infants. MethodsThe gestational age,the risk factors of cerebral palsy and clinical features of 478 children with cerebral palsy were analyzed retrospectively. ResultsFetal distress,threatened abortion,non-infectious diseases during pregnancy,hypoxic-ischemic encephalopathy,neonatal convulsion,infection of newborn,intracranial hemorrhage and haemolysis did not correlated with the gestational age of children with cerebral palsy （P0.05）. Brain malformation,maternal infection,aspiration pneumonia,neonatal asphyxia and hyperbilirubinemia negatively correlated with the gestational age （P0.05）. The incidence of spasmo-diplegia was significantly different between preterm and term infant （P0.05）. ConclusionThe morbidity of cerebral palsy associated with the merging development malformation,maternal infection,aspiration pneumonia,neonatal asphyxia or hyperbilirubinemia increased as the gestational age declined. The spasmo-diplegia more happened in the preterm infants than in the term ones.

关 键 词：脑性瘫痪 高危因素 胎龄 

分 类 号：R742.3[医药卫生—神经病学与精神病学]